This $175,888 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support the University of Maryland, College Park in a research project to study the neurogenetic mechanisms underlying nicotine and cannabis addiction. The key objectives are to: 1) Develop new transcriptome-wide association study (TWAS) methods to identify genes associated with brain functional connectivity changes linked to nicotine addiction; 2) Perform TWAS to identify genes associated with brain functional connectivity and cannabis use; and 3) Create software and a database to enable further research in this area. This project aims to advance the understanding of how genetic factors influence brain function and the development of substance use disorders, which is a critical step toward improving prevention and treatment strategies.
Generated 3/4/25, 8:20 AM