This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $268,470 to The RAND Corporation to study the impacts of cannabidiol (CBD) policies on substance use behaviors and outcomes in the United States. The key objectives are to: 1) analyze recent laws and regulations around medical CBD access, and how they fit into the broader marijuana policy landscape; 2) examine the effects of medical CBD...
This National Institute on Drug Abuse (NIDA) Project Grant, awarded under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a $376,078 study exploring the antecedents and consequences of cannabis use for coping purposes. The University of Colorado, Boulder is conducting this 5-year research project, which aims to: 1) experimentally test if cannabis use quantity increases when used for coping after stress induction; 2) examine if factors like social anxiety and inhibitory...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will support a 5-year, $1,050,000 study at West Virginia University to examine the effects of cannabidiol (CBD) on the driving performance and cognitive function of healthy adults. The study aims to determine the impact of different CBD doses on driving behavior, drowsiness, sedation, and cognitive function in a sample of 300 participants aged...
The federal Project Grant award K23DA060336, provided by the National Institute on Drug Abuse (NIDA), will fund a study on the prevalence and effects of cannabidiol (CBD) use during pregnancy. The project falls under NIDA's Drug Use and Addiction Research Programs (CFDA 93.279), which supports research aimed at understanding and addressing substance use disorders. The study, to be conducted by the University of Colorado-Denver, will have three main objectives: 1) Estimate the prevalence of CBD...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a $1,980,270 observational study to assess the neurobehavioral impacts of medical cannabis use in adults aged 35-65 in Minnesota. The key objectives are to: 1) Evaluate the effects of medical cannabis compounds on cognition, behavior, and pain relief, 2) Assess the impacts on white matter microstructure, brain function, and connectivity...
This four-year, $4.6 million project grant from the National Institute on Drug Abuse will fund research at the University of Miami exploring the linkage between cannabis use, route of administration, cannabinoid content, and measures of cardiovascular disease (CVD) risk in people living with HIV (PWH). Specifically, the principal investigator - an interventional cardiologist and physician scientist focused on HIV and CVD prevention - will collect comprehensive data on 300 PWH ages 18-60 to...
This Project Grant award of $535,374 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support research on the acute and long-term effects of cannabinoid exposure during critical periods of brain development. The University of Mississippi will use a zebrafish model system to investigate the impacts of tetrahydrocannabinol (THC) and cannabidiol (CBD) on neuroinflammation, gene/protein expression, cellular trajectories, and...
This federal Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the pathophysiological mechanisms of cannabidiol (CBD) in stress regulation. The $794,696 award, effective May 1, 2025 through February 28, 2030, will evaluate the effects of CBD on neural reactivity, limbic region influences, neuronal viability, and endocrine/behavioral stress responsivity in a clinical...
This federal Project Grant award of $153,000 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The funding will support a 6-month longitudinal study examining the relationship between naturalistic cannabis use, pain perception, and daily functioning among a sample of 60 cannabis-using young adults with chronic pain. The research will utilize an ecological momentary assessment (EMA) approach to track intraindividual...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will provide $395,995 to Oregon Health & Science University (OHSU) to conduct a longitudinal study examining the reciprocal relationships between cannabis use, sleep, and the hypothalamic-pituitary-adrenal (HPA) axis. The 5-year study will enroll 60 participants, including healthy controls, individuals with moderate cannabis use, and those with cannabis...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $541,080 to The Trustees of Columbia University in the City of New York to conduct a human laboratory study examining the effects of repeated cannabidiol (CBD) administration on the abuse-related and analgesic effects of smoked cannabis.
The key objectives of this 5-year study are to determine whether daily oral CBD administration alters: 1) the abuse-related and reinforcing effects of smoked cannabis, and 2) the analgesic (pain-relieving) effects of smoked cannabis in healthy adult cannabis smokers. The study involves randomizing 72 participants to receive different CBD doses (0, 50, 100, or 300 mg/day) for 15 days, and then assessing their responses to smoking a standardized cannabis cigarette on select days. The researchers will measure abuse-related subjective effects, pain thresholds, and self-administration of additional cannabis puffs. This study aims to provide critical data on the interaction between CBD and cannabis, as well as training for the principal investigator to become an independently funded researcher in this area.