This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $820,845 to New York University School of Medicine to conduct research aimed at improving HIV outcomes across diverse settings and subgroups in the U.S. HIV epidemic. The research will use mathematical modeling to simulate alternative ways to distribute resources across interventions, settings, and target...
This Project Grant award, funded by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), is focused on harnessing data science and machine learning to improve HIV care outcomes. The $200,000 award, effective March 1, 2025 through January 31, 2030, will support a hybrid type 2 implementation-effectiveness trial to evaluate an algorithm-driven strategy for delivering comprehensive care management and care coordination (CCM/CC) services to people...
This federal Project Grant award of $285,816 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to enhance the understanding of ADP-ribosylation (ADPR) in the biology of Human Immunodeficiency Virus 1 (HIV-1) through biochemical, proteomic, and cellular assays. The primary objectives are to: 1) Identify global proteomic changes to ADPR during HIV-1 latency and reactivation; 2) Investigate PARP-HIV-1...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to improve the health of people living with HIV (PWH). The $793,247 award will fund a 5-year research project to: 1) develop and implement a data-driven algorithm to assign validated causes for hospitalizations among PWH, 2) develop hospitalization risk scores using advanced machine learning techniques to...
This $197,366 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support research to understand the mechanisms behind the human immune system's natural restriction of a specific subset of the HIV virus. The key objectives are to: 1) Characterize the molecular mechanisms driving the restriction of X4-tropic HIV replication in the presence of R5-tropic virus, and 2) Determine the...
This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to elucidate the molecular mechanisms underlying T cell dysfunction and HIV persistence in persons with HIV (PWH). The $500,000 award, effective from September 1, 2024 to August 31, 2029, will support research conducted by The General Hospital Corporation (Massachusetts General Hospital) to identify and...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $773,365 to The Johns Hopkins University from June 2025 through May 2030. The primary objectives of this award are to: Enhance the technical rigor of implementation science research, build capacity among investigators, and facilitate networking in HIV-related implementation science. Optimize the...
This federal Project Grant award of $1,766,954.46 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the immune microenvironments that impact HIV persistence and expression during antiretroviral therapy (ART). The key objectives are to: 1) Determine the location, phenotype, and microenvironment of HIV viral RNA (vRNA)-expressing cells in secondary lymphoid tissues of...
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $781,367 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Weill Medical College of Cornell University. The grant, awarded on January 25, 2024, will support research to define and maximize the impact of CD8+ T-cell selection on the landscape of HIV integration sites. The goal is to optimize strategies for eradicating the persistent reservoir of HIV-infected cells and achieve...
This $479,925 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research at Albany College of Pharmacy and Health Sciences (ACPHS) to investigate the role of cell-to-cell transmission of HIV-1 in activating interferon (IFN) production and related signaling pathways in human immune cells. The key objectives are to: 1) Determine whether HIV-1 cell-to-cell transmission activates IFN production...