Project Grant K01AG092933
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. received a Project Grant award of $155,504 from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective March 1, 2026, with completion by September 7, 2027. This research initiative investigates the relationship between body composition, physical activity, and cognitive function in adults with Down syndrome (DS), a population with approximately a 90% lifetime...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Pennington Biomedical Research Center a $749,481 Project Grant (CFDA 93.866, Aging Research) effective January 1, 2026, through December 31, 2030, to conduct a lifestyle intervention research study. The project will deliver a 12-week randomized controlled feeding trial examining the effects of a low-energy-density diet combined with exercise on fat mass reduction, muscle function improvement, and energy deficit...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded New York University School of Medicine a $3.55 million Project Grant under the Aging Research program (CFDA 93.866) to investigate the curse of choice phenomenon in elderly populations, particularly those experiencing cognitive decline. The four-year project, initiated July 15, 2026, and concluding June 30, 2030, delivers a comprehensive research program examining how decision quality deteriorates as the number...
- Federal Grant Award Summary Award: K63 Polyubiquitination as a Mechanism Linking Obesity and Age-Related Memory Decline Funding Agency & Program: National Institute on Aging (NIA), Aging Research (CFDA 93.866) Award Amount & Period: $409,464 obligated; May 15, 2026 – April 30, 2027 Products and Services Delivered: Virginia Polytechnic Institute & State University (Virginia Tech) will conduct biomedical research investigating the molecular mechanisms linking obesity and aging to...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Wake Forest University Health Sciences a $3.16 million Project Grant under the Aging Research program (CFDA 93.866) effective June 1, 2026, through May 31, 2030, to conduct research examining the effects of caloric restriction on aging biomarkers, frailty, and multimorbidity in obese older adults. The research will determine whether short-term caloric restriction affects a consensus-derived blood-based biomarker index...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $2.003 million Project Grant to the University of Pittsburgh under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This award funds research to characterize white matter injury in Alzheimer's disease (AD) and its role in cognitive decline. The study employs a novel, spatially precise neuroimaging methodology called Unhealthy White Matter Connectivity (UWMC) to...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $115,076 to the University of Illinois (Board of Trustees) on December 10, 2025, under the Aging Research program (CFDA 93.866). The award funds research examining the relationship between purpose in life (PIL), physical activity (PA), and cognitive function among older adults with cognitive impairment (OACI), particularly those with Alzheimer's disease and related dementias. The research aims to address...
- Federal Grant Award Summary Northwestern University's Sponsored Research Division received a $1.34 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective February 15, 2026, through November 30, 2030. This award supports continuation of a longitudinal cohort study examining aging-in-place and long-term care (AIP/LTC) decision-making and implementation among older adults with Alzheimer's dementia. The project follows 293...
- Federal Project Grant Summary New York University School of Medicine received a $6.2 million Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 15, 2025 through May 31, 2030. The research initiative, titled "Peripheral Immunity and the Aging Brain," investigates the relationship between circulating vascular and immune dysfunction markers—specifically platelet aggregation and neutrophil activity—and...
- Federal Grant Award Summary The National Institute on Aging awarded a $656,829 Project Grant to the University of Rochester effective January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the selective vulnerability of the fronto-insular network (FIN) in aging and Alzheimer's disease (AD). The five-year research initiative, concluding December 31, 2030, combines in vivo structural, functional, and molecular analyses with behavioral assessments in mouse models to...
The National Institute on Aging (NIA) awarded a $137,245 Project Grant to New York University School of Medicine on July 15, 2026, under the Aging Research program (CFDA 93.866). This research project, scheduled for completion on April 30, 2031, investigates the obesity paradox phenomenon observed in older end-stage kidney disease (ESKD) patients with cognitive impairment and dementia/Alzheimer's disease (AD). The award supports a comprehensive research initiative that examines whether enhanced anthropometric and body composition measures—beyond standard body mass index (BMI)—are associated with cognitive decline and dementia/AD diagnosis, and whether intentional weight loss prevents cognitive deterioration in this patient population. The project leverages an existing National Institute on Aging-funded prospective cohort of 2,700 ESKD patients and incorporates a pilot study at an obesity management clinic to overcome methodological limitations of prior research. Deliverables include research findings from three coordinated study aims addressing the relationship between obesity measures and cognitive outcomes, peer-reviewed publications, and training outcomes in dementia/AD, cognition, obesity management, and aging through a structured coursework and clinical apprenticeship program. This research addresses a critical gap in understanding why obesity appears protective against dementia/AD in ESKD patients—contrary to findings in community-dwelling older adults—to inform prevention and treatment strategies for a vulnerable population with elevated dementia risk.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $137.2k | 7/14/26 |