This $2,557,260 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will fund a 5-year study by the University of California, San Francisco (UCSF) to investigate the transition from midlife to early late-life and identify early predictors and mechanisms of Alzheimer's disease and related dementias (ADRD) among Black and White adults in their 60s. The study will leverage the long-running Coronary Artery Risk Development in Young Adults (CARDIA) cohort to...
This Project Grant award, titled "BRIDGING SOCIAL EPIDEMIOLOGY AND POLICY FOR ADRD PREVENTION: EFFECTS OF POVERTY ALLEVIATION POLICIES ON ALZHEIMER'S DISEASE AND RELATED DEMENTIAS RISK AND DISPARITIES," is funded by the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $131,813. The award will support research to evaluate the effects of poverty alleviation policies, such as the Supplemental Nutrition Assistance Program (SNAP), on the prevalence of...
The National Institute on Aging awarded a $197,747 Project Grant (CFDA 93.866) to The Regents of the University of California, San Francisco to conduct a mixed-methods investigation on the impact of structural gendered racism on cognitive aging and Alzheimer's disease risk among Black women. The study aims to: 1) develop and validate a multidimensional index of structural gendered racism, 2) identify distinct latent class profiles of structural gendered racism, and 3) examine the associations...
This federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) in the amount of $319,000 will support research to examine rural-urban and within-rural disparities in Alzheimer's disease and related dementias (AD/ADRD) in the United States. The 2-year project, led by an early-stage investigator at Brown University, aims to 1) produce robust estimates of dementia prevalence in rural and urban areas, and 2) characterize the types of rural places and...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a multimodal neuroimaging study to investigate sex-based differences in brain circuitry and their relationship to Alzheimer's disease pathology. The $815,215 project, which runs from May 2025 to February 2030, will leverage a new prospective cohort and open-source datasets to assess the impact of sex and sex-based factors, such as reproductive period and APOE genotype, on functional brain...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a comprehensive scientific investigation into the role of reproductive aging and racial disparities in the development of Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). The $131,004 award to The Leland Stanford Junior University will fund research to assess how earlier menopause and reproductive surgeries may contribute to the higher risk and prevalence of...
The National Institute on Aging (NIA) awarded a $4,787,820 Project Grant (CFDA 93.866 - Aging Research) to Brown University to conduct research on predicting the effects of diagnosis in individuals across countries and time for Alzheimer's disease and related dementias (ADRD). The 3-year project, starting on September 20, 2024 and ending on August 31, 2027, aims to: Examine whether older adults experiencing cognitive decline during their working life are more likely to experience an earlier,...
This $1,820,685.15 federal Project Grant award, made by the National Institute on Aging (CFDA 93.866 Aging Research program), will fund a project at Vanderbilt University Medical Center to systematically screen and validate drug repurposing candidates for Alzheimer's disease and related dementias (AD/ADRD). The project aims to integrate genetics, transcriptomics, literature, and clinical data using advanced informatic technologies to develop and share tools to screen, prioritize, and validate...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) aims to advance health equity in the use of novel treatments for Alzheimer's disease and related dementias (ADRD). The $322,286 award to The Johns Hopkins University will fund a two-phase project. In the planning phase (R61), the researchers will conduct focus groups to understand medication decision-making processes of diverse individuals affected by ADRD. They will then design discrete choice experiments...
This federal Project Grant award, valued at $185,913, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of the grant is to examine sex-specific effects on white matter integrity and brain function in familial Alzheimer's disease (AD) and vascular dementia (VCID). The overarching goal is to use measures of white matter integrity and functional...