Project Grant HT9425261E392
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $319,800 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective November 1, 2025, through October 31, 2028. The award funds research on novel hypoxia-inducible factor 2 (HIF-2) regulators and therapeutic targets for kidney cancer, conducted at the institution's Dallas, Texas campus. This research initiative...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $323,700 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective November 1, 2025, through October 31, 2028. This award supports research utilizing enhancer CRISPR screening to identify PLXNA1 as a critical regulator in clear cell renal cell carcinoma (ccRCC). The research represents a translational science initiative aligned...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $1.31M Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds the development of next-generation renal cell carcinoma (RCC) mouse models designed to reproduce human oncogenotypes, with the ultimate objective of advancing therapeutic development and clinical...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $1,062,400 project grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective November 1, 2025, through October 31, 2029. The award supports research to identify NEK5 as a hidden driver in kidney cancer, advancing biomedical innovations relevant to military health priorities and public health objectives. As a leading academic...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $319,693 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective May 1, 2025 through July 31, 2027. The award supports research focused on dissecting the mechanism of selective HIF-2 regulation of PTHRP and hypercalcemia in clear cell renal carcinoma. This biomedical research project aims to advance understanding of...
- The Defense Health Agency (DHA) awarded a $1.297M Project Grant to The University of Texas Southwestern Medical Center under the Military Medical Research and Development program (CFDA 12.420) for a four-year research initiative beginning September 1, 2025. This award supports research to identify immunomodulatory targets of TAZ/SRF (transcriptional cofactors) in sarcomatoid renal cell carcinoma progression. The research deliverables include hypothesis-driven investigations, biomarker discovery,...
- The University of Texas Health Science Center at Houston received a $544,892 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective August 1, 2025 through July 31, 2028. The award supports research and development of a novel peptide-drug conjugate designed to enable precision-targeted DNA damage in neuroendocrine tumors. This research initiative represents the DHA's investment in transforming healthcare for...
- The University of Texas Southwestern Medical Center was awarded a $2,641,871 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant will fund research from May 1, 2023 through April 30, 2027 to comprehensively upregulate and stabilize frataxin mRNA using antisense oligonucleotides. The goal of this research is to transform health care for service members and the public by investigating medical solutions for the...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $450,174 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025, through August 31, 2030. This award, titled "Building on the Foundation of the Academy of Kidney Cancer Investigators," supports biomedical research initiatives focused on kidney cancer investigation. The Military Medical...
- The Defense Health Agency awarded a $492,927 Project Grant to The University of Texas Southwestern Medical Center in Dallas, Texas to conduct research on leveraging biophysicochemical motifs in T-cell receptor antigen binding regions and antigen co-occurrence to predict response to immune checkpoint inhibitors. This 3-year grant is part of the Military Medical Research and Development program (CFDA 12.420), which supports basic, applied, and advanced biomedical research to transform health...
The University of Texas Southwestern Medical Center received a $490,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective August 1, 2026, through July 31, 2029. The grant supports investigator-initiated biomedical research focused on harnessing the unfolded protein response as a therapeutic approach for treating rare choroid plexus carcinoma. This three-year award will be performed at the institution's Dallas, TX campus and contributes to the DHA's broader portfolio of research addressing Service Member health and conditions affecting the military population. Under this award, the institution will conduct basic and translational research activities to develop and evaluate novel therapeutic strategies targeting the unfolded protein response pathway in choroid plexus carcinoma, a rare malignancy with limited treatment options. The research aligns with the Military Medical Research and Development program's mission to transform healthcare through innovative biomedical research and advance medical solutions applicable to military and civilian populations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $490.0k | 7/13/26 |