Project Grant HT9425261E219
- Federal Grant Award Summary The University of Michigan's Regents, through its Office of Research and Sponsored Projects, received a $932,498 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for a two-year period from June 1, 2025, through May 31, 2027. The research initiative focuses on developing non-invasive central nervous system (CNS) delivery mechanisms for immunocytokines designed to sustain expansion of regulatory T...
- Federal Grant Award Summary The University of Michigan's Office of Research and Sponsored Projects received a $320,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025, through August 31, 2027. The award supports research investigating the impact of the integrated stress response on visual synaptic circuits in multiple sclerosis (MS). This research endeavor will be conducted at the...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded the Regents of the University of Michigan a $1.17 million Project Grant under the Military Medical Research and Development program (CFDA 12.420) to develop systemically administered bispecific antibodies that activate neurotrophin receptors for treating noise-induced inner ear damage. The award, effective May 15, 2025, through May 14, 2028, supports advanced biomedical research designed to address hearing loss resulting from...
- Federal Grant Award Summary The University of Michigan's Office of Research and Sponsored Projects received a $248,156 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period October 1, 2025 through September 30, 2027. The award supports research focused on identifying molecular biomarkers for invasive glioblastoma cell states and tumor microenvironment modulation. This research initiative will be conducted at...
- Federal Grant Award Summary The University of Michigan's Office of Research and Sponsored Projects received a $405,600 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025, through July 31, 2027. The award supports research on retinal repair via viral-mediated endogenous reprogramming of Müller glia cells, conducted at the University of Michigan's Ann Arbor campus. This research initiative...
- Federal Project Grant Award Summary The University of Michigan's Office of Research and Sponsored Projects received a $1.7 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for a three-year performance period running from July 1, 2026, through June 30, 2029. The award funds research focused on targeted disruption of the ARP300 enhanceosome in prostate cancer using domain-alteration chimeras (DALTACs), representing...
- Federal Grant Award Summary The University of Michigan's Office of Research and Sponsored Projects has received a $1.396 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2026 through June 30, 2029. The award supports clinical validation of a plasma circulating tumor DNA (ctDNA) assay for diffuse midline glioma (DMG) diagnosis and surveillance. This research initiative contributes to the DHA's...
- Federal Grant Award Summary The University of Michigan received a $624,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) on July 15, 2025, with completion anticipated by July 14, 2027. The award supports research investigating "The Role of Epithelial AIM2 in Helicobacter pylori-Associated Gastric Preneoplasia," conducted at the institution's Ann Arbor, Michigan campus. This research project contributes...
- Federal Grant Award Summary The University of Michigan's Regents received a $1.84 million Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025 through August 31, 2028. The award supports research focused on co-targeting NSD1/2 paralogs in androgen receptor (AR)-driven castration-resistant prostate cancer. This research initiative represents a translational oncology effort designed to advance...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded the Regents of the University of Michigan a $559,046 Project Grant under the Military Medical Research and Development program (CFDA 12.420) for the period June 1, 2026 through May 31, 2028. The award funds research investigating biased protein phosphatase 2A heterotrimerization in the development and treatment of uveal melanoma. This hypothesis-driven research initiative is expected to advance understanding of...
The University of Michigan received a $838,945 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2026 through June 30, 2028. The award supports research investigating selective pharmacological cochaperones to address TDP43-dependent disease mechanisms in amyotrophic lateral sclerosis (ALS). This research effort will be conducted at the University of Michigan's Ann Arbor campus and aims to advance therapeutic development for neurodegenerative disease through hypothesis-driven biomedical research aligned with DHA priorities in medical innovation. The research deliverables under this award include the identification and evaluation of novel cochaperone compounds targeting TDP43 pathology, translational research findings applicable to ALS treatment development, and associated publications or research outputs documenting the scientific discoveries. As part of the DHA's Military Medical Research and Development program portfolio, this award contributes to the broader federal objective of transforming healthcare through innovative medical solutions and advancing therapeutic options for critical health challenges affecting both military service members and the general public.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $838.9k | 5/18/26 |