Project Grant HT9425261E181
- Federal Grant Award Summary The Scripps Research Institute received a $718,032 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period of July 1, 2025 through June 30, 2027. The award supports research targeting glycoimmune checkpoints Siglec-7 and -9 for the treatment of colorectal cancer. This research represents an application of advanced biomedical science to develop novel therapeutic interventions addressing...
- The Department of Defense's Military Medical Research and Development program (CFDA 12.420) has awarded Scripps Research Institute, a nonprofit biomedical research organization, a $529,125 project grant to investigate microglia dysfunction in MEF2C deficiency autism spectrum disorder with the goal of discovering targeted therapies. This 3-year award, effective September 30, 2024, will fund research aimed at improving the health and care of military service members, veterans, and their families...
- Federal Grant Award Summary The Scripps Research Institute received a $300,000 Project Grant award from the Research Development and Engineering Command under the Basic Scientific Research program (CFDA 12.431) on August 15, 2025, with a completion date of August 14, 2030. The award supports research into genetically encoded, new-to-nature ligands with designer bioactivities, representing fundamental scientific investigation aimed at advancing long-term national security needs. As a leading...
- This federal Project Grant award from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research to investigate the molecular mechanisms of APOE4 vulnerability to Alzheimer's disease and identify novel therapeutic targets. The $999,975.63 award to the Icahn School of Medicine at Mount Sinai in New York, NY aims to transform healthcare for military service members, veterans, and the broader public through innovative and impactful medical...
- Federal Project Grant Award Summary Sanford Burnham Prebys Medical Discovery Institute received a $1,078,882 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective May 1, 2025, through April 30, 2027. The award supports research applying chemical engineering approaches to amyotrophic lateral sclerosis (ALS) treatment, with a focus on advancing understanding of the multimodal therapeutic actions of donor and host neural...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded a $993,283 Project Grant to The Regents of the University of California, San Francisco under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025 through August 31, 2027. The award supports research into the proteomic determinants and components of progression in multiple sclerosis. This research initiative aligns with the DHA's mission to transform healthcare for service members...
- This federal Project Grant award in the amount of $811,942 was provided by the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research by the J. David Gladstone Institutes, a non-profit biomedical research organization, to investigate genetic factors conferring susceptibility to toxicant-induced Parkinson's disease. The research involves a sub-award to the Northern California Institute For Research And...
- The Defense Health Agency awarded a $365,623 Project Grant under the Military Medical Research and Development (CFDA 12.420) program to Fundacio De Recerca Clinic Barcelona-Institut D'investigacions Biomediques August Pi I Sunyer, a non-profit biomedical research organization in Barcelona, Spain. The grant, awarded on September 1, 2024, will support the development of a novel blood-based diagnostic test to detect alpha-synuclein aggregation as an indicator of Parkinson's disease. The...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $999,999 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025, through July 31, 2028. This award supports the development and validation of cell-free deoxyribonucleic acid (DNA) epigenetic biomarkers for multiple sclerosis, a three-year research initiative conducted at UCSF's San Francisco facility. The project...
- Federal Grant Award Summary Children's Research Institute received a $777,659 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period August 1, 2025 through July 31, 2028. The award supports research titled "Use of ProResolution and Restorative Pharmacology Approaches for DMD Therapy," focusing on the development of innovative therapeutic interventions for Duchenne muscular dystrophy (DMD). The...
The Scripps Research Institute received a $769,972 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period of August 1, 2026, through July 31, 2029. The grant supports research investigating redox-mediated neurotoxicity associated with military-related toxic exposures in the context of Parkinson's Disease. The research will leverage Scripps' interdisciplinary capabilities in chemistry, biology, and computational science to advance understanding of disease mechanisms and identify potential therapeutic interventions relevant to military service members' health. As a leading biomedical research organization, Scripps Research Institute will deliver hypothesis-driven research and development services designed to understand the complex biological pathways linking toxic exposures to neurodegeneration. The award supports the institute's scientific expertise in developing research methodologies, conducting advanced biomedical investigations, and translating findings toward therapeutic development. This research aligns with the Military Medical Research and Development program's emphasis on innovative solutions addressing critical health challenges affecting military personnel and the broader American public.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $770.0k | 6/9/26 |