Project Grant HT9425261E155
- Federal Project Grant Summary The University of Massachusetts Medical School received a $670,000 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded September 1, 2025, with completion targeted for August 31, 2029. The award supports research to identify immunomodulatory targets of TAZ/SRF (transcriptional co-activators/serum response factor) in sarcomatoid renal cell carcinoma progression. This four-year initiative...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $3.854 million Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025, through August 31, 2029. The project, titled "Targeting Human Respiratory Viruses and Host Sequences with Respiratory-Active RNAs," supports advanced biomedical research aimed at developing innovative approaches to address...
- Federal Project Grant Award Summary Dana-Farber Cancer Institute, Inc. (DFCI) received a $2.0 million project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded September 30, 2026, with a performance period extending through September 29, 2030. The award supports the Prostate Cancer Clinical Trials Consortium, which will be conducted at DFCI's Boston, Massachusetts location. Under this funding mechanism, DFCI will deliver...
- Summary of Federal Project Grant Award The University of Massachusetts Medical School received a $952,162 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period August 1, 2025 through July 31, 2027. The award supports the development of novel, improved adeno-associated virus (AAV) vectors for the treatment of amyotrophic lateral sclerosis (ALS). Research activities will be conducted at the institution's...
- Federal Project Grant Award Summary The University of California, San Francisco (UCSF) received a $1.23 million Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) on September 30, 2025, with a completion date of September 29, 2029. The award supports research to validate CD46 as a promising biomarker in advanced prostate cancer, aligning with the DHA's mission to transform healthcare for service members and the...
- Federal Grant Award Summary Award Overview Harvard T.H. Chan School of Public Health received a $539,904 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on genomically informed morphological stromal signatures to predict lethal prostate cancer. The award was obligated on June 15, 2025, with a completion date of June 14, 2028, providing a three-year performance period for this biomedical research...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded a $235,476 project grant to the University of California, Los Angeles (UCLA) Office of Research Administration on November 1, 2025, to develop new cell-mediated immunotherapeutic strategies for neuroendocrine prostate cancer. The two-year award, which concludes October 31, 2027, is funded under the Military Medical Research and Development program (CFDA 12.420) and will be conducted at UCLA's Los Angeles, California facility....
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1.54M project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds research activities focused on assessing prognoses and validating surrogate endpoints for clinical outcomes in metastatic hormone-sensitive prostate cancer. This research initiative aligns with the Defense...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded Massachusetts General Hospital (MGH) a $1.35M Project Grant under the Military Medical Research and Development program (CFDA 12.420) effective July 1, 2025 through June 30, 2029. The award funds research investigating metabolites and metabolic pathways in relation to Crohn disease risk, with research activities conducted at MGH's Boston, Massachusetts location. This biomedical research initiative aligns with the DHA's...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded Massachusetts General Hospital a $3.5 million Project Grant under the Military Medical Research and Development program (CFDA 12.420) effective July 1, 2026 through June 30, 2030. The award supports development and validation of the HEP B-HOST Junction Test, a blood-based biomarker assay designed for early detection of primary and recurrent hepatitis B-related hepatocellular carcinoma. This research initiative aligns with the...
The University of Massachusetts Medical School received a $1.7 million project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the three-year period from July 1, 2026, through June 30, 2029. The award funds hypothesis-driven biomedical research to determine the contribution of interferon gamma signaling to neuroendocrine prostate cancer progression and immunotherapy resistance. This research addresses a critical gap in understanding mechanisms of treatment resistance in advanced prostate cancer, with implications for improving therapeutic outcomes for military service members and the broader American public. Under this project grant, the University of Massachusetts Medical School will deliver research and development services, including mechanistic studies of interferon gamma signaling pathways, biomarker discovery related to neuroendocrine differentiation and immunotherapy response, and translational findings applicable to prostate cancer therapeutic development. The work will be performed at the institution's Worcester, Massachusetts location, leveraging its established research infrastructure and expertise in cancer biology and immunotherapy research within the DHA's competitive, peer-reviewed funding portfolio.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.7m | 5/3/26 |