Project Grant HT9425261E132
- Federal Project Grant Award Summary Yale University received a $527,262 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2026, through June 30, 2029. The award funds research titled "Harnessing Myeloid Cell Ontogeny to Prevent Melanoma Brain Metastasis," to be conducted at Yale's New Haven, Connecticut campus. This project represents a hypothesis-driven biomedical research initiative designed...
- Federal Project Grant Award Summary Yale University received a $522,736 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2026 through June 30, 2029. The award supports research titled "Harnessing Myeloid Cell Ontogeny to Prevent Melanoma Brain Metastasis," to be conducted at Yale's New Haven, Connecticut facility. Under this award, Yale will deliver hypothesis-driven biomedical research and...
- Federal Grant Award Summary Yale University received a $559,992 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded July 1, 2026, with an ultimate completion date of June 30, 2028. The research project, titled "Biological Role and Therapeutic Targeting of HLA Class I Antigen Processing Machinery Dysregulation in Human Non-Small Cell Lung Cancer Brain Metastases," will be conducted at Yale's New Haven,...
- Federal Grant Award Summary Yale University received a $1.25 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2026 through June 30, 2029. The grant supports research targeting KDM5 histone demethylases as a therapeutic approach to treat breast cancer. This research initiative aligns with the DHA's mission to transform healthcare for service members and the American public through innovative...
- Federal Grant Award Summary Yale University received a $670,917 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective June 15, 2025, through June 14, 2027. The award supports research titled "Exploiting METTL3 Inhibition-Induced Dysregulation of DNA Repair in the Treatment of Leukemia," conducted at Yale's Hamden, Connecticut location. This research project investigates novel therapeutic...
- Federal Grant Award Summary Yale University received a $1.675 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 15, 2025 through August 14, 2029. The award funds research and development activities focused on drug discovery for dystonia and frontotemporal degeneration, two neurodegenerative conditions of significant medical concern. Research will be conducted at Yale's New Haven, Connecticut...
- Federal Grant Award Summary Yale University received a $1,005,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for a four-year research initiative focused on mast cell therapy for ovarian cancer. The award, effective June 15, 2025 through June 14, 2029, supports biomedical research aimed at developing novel therapeutic interventions to address cancer treatment challenges relevant to military service members and the...
- Federal Grant Award Summary Yale University received a $1,004,472 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded on June 15, 2025, with a completion date of June 14, 2029. The project, titled "Mast Cell Therapy for Ovarian Cancer," is being conducted at Yale's Hamden, Connecticut facility. This award supports advanced biomedical research aimed at developing innovative therapeutic interventions for...
- Federal Grant Award Summary Yale University received a $705,038 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2025 through June 30, 2029. The award supports the development of GUAR-T as a novel class of universal cellular immunotherapies for ovarian cancer treatment. This research initiative represents a translational effort to advance innovative immunotherapeutic approaches that address critical...
- Federal Project Grant Award Summary Yale University received a $1,009,054 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025 through August 31, 2029. The award supports research focused on the discovery and therapeutic targeting of endogenous retroviruses in clear cell renal cell carcinoma. This biomedical research initiative addresses cancer treatment through investigation of endogenous...
Yale University received a $1.05M project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to support research on harnessing myeloid cell ontogeny to prevent melanoma brain metastasis. The award, dated July 1, 2026, will be performed at Yale's New Haven, Connecticut location through June 30, 2029. This three-year research initiative aligns with the DHA's broader portfolio of hypothesis-driven biomedical research designed to advance healthcare solutions for military service members and the general public, with particular emphasis on cancer immunotherapy and precision medicine approaches. The funded research will deliver translational science and biomedical research services focused on understanding myeloid cell development and function as a mechanism to prevent the spread of melanoma to the brain. As part of the Military Medical Research and Development program's two-tier competitive review process, this project was evaluated for both technical merit and military relevance before funding authorization. The grant represents Yale's established capacity in delivering complex biomedical research and oncology-focused investigations consistent with the institution's active federal research portfolio across the National Institutes of Health, National Science Foundation, and Department of Defense funding mechanisms.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 4/29/26 |