Project Grant HT9425261E130
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $349,976 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2026, through June 30, 2028. The award funds research focused on intercepting omental metastasis of ovarian cancer by targeting a mitochondrial redox-interleukin-10 (IL-10) axis in the immune microenvironment. This translational research initiative...
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $1,099,986 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded on June 1, 2026, with a completion date of May 31, 2030. The award funds research focused on metabolic rewiring of chimeric antigen receptor T (CAR-T) cells to overcome the hostile tumor microenvironment in pancreatic cancer. This four-year research...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $347,581 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period of June 1, 2026, through May 31, 2028. The award supports research investigating ovarian cancer dormancy induced by metabolic alterations, a translational research initiative aligned with the DHA's mission to advance innovative biomedical solutions for...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $490,500 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025, through August 31, 2028. The grant funds research combining TROP2-directed chimeric antigen receptor natural killer (CAR-NK) cells with HIF2A (hypoxia-inducible factor 2-alpha) inhibition to develop novel immunotherapy approaches for pancreatic...
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $735,751 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025, through August 31, 2028. The award supports research and development activities focused on combining TROP2-directed chimeric antigen receptor natural killer (CAR-NK) cells with HIF2A (hypoxia-inducible factor 2-alpha) inhibition as an...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $489,767 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective October 1, 2025, through September 30, 2028. The award supports research titled "Building T-Cell Products in NF1-Associated MPNST Through Antigen Discovery and Epigenome Targeting," which addresses the development of therapeutic T-cell immunotherapy...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $893,525 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award supports research targeting neuronal mimicry in SMARCB1-deficient renal medullary carcinoma treatment. This three-year initiative will deliver translational and clinical research services focused on developing...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $1.35 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the three-year period from October 1, 2025, through September 30, 2028. The award funds research focused on building T-cell products for neurofibromatosis type 1 (NF1)-associated malignant peripheral nerve sheath tumors (MPNST) through antigen discovery and...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $414,472 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025 through August 31, 2028. The award funds research targeting neuronal mimicry mechanisms in SMARCB1-deficient renal medullary carcinoma treatment. This research represents a translational oncology initiative designed to advance therapeutic...
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $817,496 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds research to investigate the PRMT3-IGF2BP1 axis-mediated epitranscriptomic reprogramming as a novel therapeutic strategy to overcome immunotherapy resistance in clear cell renal cell carcinoma...
The University of Texas MD Anderson Cancer Center received a $349,996 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period June 15, 2026 through June 14, 2028. The award funds research on metabolic rewiring of chimeric antigen receptor (CAR)-T cells to counter the hostile tumor microenvironment in ovarian cancer. This research aims to develop enhanced immunotherapy approaches by modifying the metabolic pathways of CAR-T cells, enabling them to function more effectively within the immunosuppressive environment of ovarian tumors. MD Anderson will deliver translational research and development services focused on advancing CAR-T cell engineering and optimization for ovarian cancer treatment. As a National Cancer Institute-designated Comprehensive Cancer Center with extensive experience in federal cancer research funding, MD Anderson's multidisciplinary teams of clinicians and physician-scientists will conduct basic and applied research to support the development of more effective cellular immunotherapies. The award reflects the DHA's investment in innovative biomedical research solutions with potential military and civilian healthcare applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $350.0k | 6/9/26 |