Project Grant HT9425261E125
- Federal Grant Award Summary Georgetown University received a $780,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded June 15, 2025, with an ultimate completion date of June 14, 2028. The award supports research investigating environmentally induced sperm ribonucleic acids (RNAs) as mediators of placentation, progeny, and maternal health. This three-year research initiative will be conducted at Georgetown...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded The Washington University a $699,751 Project Grant under the Military Medical Research and Development program (CFDA 12.420) on May 1, 2026, with a completion date of April 30, 2029. The award funds research to unveil mechanisms and develop innovative therapeutic interventions targeting ESR1-CCDC170 fusions in clinically aggressive, endocrine-resistant, and metastatic breast cancers. This research initiative represents the DHA's...
- Federal Project Grant Award Summary Thomas Jefferson University, operating as Sidney Kimmel Medical College, received a $1,998,484 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) beginning September 1, 2026 and concluding August 31, 2029. The award funds a three-year research initiative titled "Deciphering the Role of PIK3CA Mutations in Tumorigenesis of HER2-Positive Breast Cancer," to be conducted at the...
- Federal Project Grant Award Summary Columbia University's Health Sciences Division received a $750,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) with a performance period from July 1, 2026 through June 30, 2029. The award funds research to identify novel therapeutic targets that overcome treatment resistance in triple-negative breast cancer (TNBC), a particularly aggressive form of cancer with limited...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded The Wistar Institute of Anatomy and Biology a $750,000 project grant under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2026 through June 30, 2029. The award supports the development of novel biologic therapeutics targeting Siglec-7/9 receptors designed to activate and engage natural killer (NK) cells and macrophages for the treatment of advanced breast cancer. This research...
- Federal Grant Award Summary George Mason University received a $501,515 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2026, through August 31, 2029. The award supports research to decipher the role of PIK3CA mutations in tumorigenesis of HER2-positive breast cancer. This investigation contributes to the DHA's broader mission of transforming healthcare for service members and the American...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center was awarded $493,020 by the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the project "Targeting WNK1 to Disrupt Cell Volume Control in Triple-Negative Breast Cancer." The award is effective July 1, 2026, through June 30, 2029. This project grant funds hypothesis-driven biomedical research designed to develop innovative therapeutic...
- Federal Grant Award Summary The Washington University's Office of Sponsored Research Services received a $894,125 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to support research titled "Understanding and Targeting Epigenetic Vulnerabilities in NF-1-MPNST." The three-year award, effective from July 15, 2025 through July 14, 2028, funds advanced biomedical research investigating epigenetic mechanisms and...
- Federal Grant Award Summary The University of Washington received a $1,494,943 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective April 1, 2026 through March 31, 2029. The award supports research and development services focused on biomaterial strategies to improve the specificity and efficacy of Chimeric Antigen Receptor (CAR) T cell therapy for breast cancer treatment. This research initiative aligns...
- Federal Grant Award Summary The Geneva Foundation received a $488,276 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective April 1, 2026 through March 31, 2029. This research initiative focuses on developing antagonism-enforced braking system CAR T-cells (chimeric antigen receptor T-cell therapy) for the treatment of TP53-mutant breast cancer. The project represents DHA's commitment to advancing innovative...
Georgetown University received a $754,873 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) with an award date of July 1, 2026, and a completion date of June 30, 2029. The research initiative, titled "Targeting WNK1 to Disrupt Cell Volume Control in Triple-Negative Breast Cancer," focuses on investigating the role of the WNK1 protein in regulating cellular volume mechanisms within triple-negative breast cancer cells. This project represents a hypothesis-driven biomedical research effort designed to advance innovative therapeutic strategies for cancer treatment, aligning with the Defense Health Agency's mission to transform healthcare for service members and the American public through targeted medical research. The award supports basic and translational research activities to be conducted at Georgetown University's Washington, D.C. campus. As a major research institution with extensive experience in Defense Health Agency-funded oncology research, Georgetown will deliver research and development services including laboratory investigations, data analysis, and scientific findings that contribute to the broader portfolio of cancer immunotherapy and precision medicine initiatives funded under the Military Medical Research and Development program. The three-year performance period allows for comprehensive investigation into cellular mechanisms that could inform future therapeutic interventions for triple-negative breast cancer, a particularly aggressive form of breast malignancy.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $754.9k | 4/21/26 |