The Department of the Army Medical Command awarded a $1,234,505.00 Project Grant under the Military Medical Research and Development (CFDA 12.420) program to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), for the project "COTARGETING THE TUMOR MICROENVIRONMENT TO REVOLUTIONIZE ANTIBODY-DRUG CONJUGATE THERAPY FOR REFRACTORY BREAST CANCERS". The award, which runs from March 1, 2025 to February 29, 2028, will support advanced biomedical...
The Department of the Army Medical Command has awarded a $1,644,309 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The award, which runs from February 1, 2025, to January 31, 2028, will fund research aimed at "FUNCTIONAL MOLECULAR NETWORKS MODIFYING HIF2A ACTIVITY IN VHL TUMORS." As a renowned academic medical center and major recipient of federal...
The Department of the Army Medical Command, through the Military Medical Research and Development (CFDA 12.420) federal grant program, awarded a $1,498,368 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), with a performance period from August 1, 2024 to July 31, 2027. The grant supports research to elucidate the molecular mechanisms of tumor-immune dynamics and evolution in response to radiation, in order to optimize treatment of high-...
The Massachusetts General Hospital will receive $408,816 under a two-year Project Grant award from the Defense Health Agency to support research on structural biology-informed optimization of antibody-drug conjugates for ovarian cancer. The goal is to minimize toxicity through this work. This award falls under the Military Medical Research and Development program (CFDA 12.420), which supports basic, applied, and advanced biomedical research to transform military and public health care. The...
The Defense Health Agency awarded a $732,825 Project Grant to The General Hospital Corporation (Massachusetts General Hospital) under the Military Medical Research and Development program (CFDA 12.420) for an extension of an artificial chromosome-based system as a novel delivery strategy for CAR-T cell therapy of ovarian cancer to human lymphocytes. This 3-year project, running from September 1, 2023 to August 31, 2026, aims to develop and validate new treatment approaches for ovarian cancer. As...
The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), was awarded a $577,094 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct research aimed at "Redirecting Viral Immunity to Eradicate Low Tumor Mutation Burden Lung Cancers." The award period runs from Aug 31, 2023 to Aug 29, 2025. As a leading academic medical center and research institution, MGH utilizes its...
The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), has been awarded a $1,000,236.00 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420). The grant, effective April 1, 2024 through March 31, 2028, will fund research to "UNLOCK THE CTDNA MUTATIONAL PATTERNS FOR EARLY CANCER DETECTION AND NONINVASIVE BIOMARKERS." As a leading academic medical center and research...
The Department of the Army Medical Command awarded a $888,632 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on "Deciphering the Role of Maternal Autoantibodies in the Induction of Offspring Behavioral Abnormalities Following Maternal TLR7 Activation." The award period is from April 1, 2025 to March 31, 2027. MGH, a renowned nonprofit...
The federal Project Grant award, totaling $1,270,020.00, was provided by the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) program. The award to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), supports the "Development of Personalized Cancer Vaccines Targeting Tumor Heterogeneity and Reprogramming the Cold Tumor Micro-environment in Kidney Cancer." This 4-year research project aims to...
The U.S. Department of the Army Medical Command awarded The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), a $443,170 Project Grant under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant supports the development of a transgene expression control switch for Friedreich ataxia gene therapies. This research aims to advance disease prevention, diagnosis, treatment, and management through basic, applied, and...