Project Grant HT94252410202

Award Date 4/1/24
Completion Date 3/31/28
Dollars Obligated $1.4M
Federal Grant Program
12.420
Assistance Type
Project Grant
Place of Performance
San Antonio, TX 78229, USA
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The University of Texas Health Science Center at San Antonio (UTHSCSA) was awarded a $1,116,000 Project Grant by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420). The award supports a research project titled "ROLE OF PODOCYTE CERAMIDE SYNTHASE 6 IN FSGS" with a performance period from Apr 1, 2024 to Mar 31, 2028. The project aims to investigate the role of a specific protein, ceramide synthase 6, in the development...
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This federal Project Grant award of $1,442,061.00, awarded on April 1, 2024 by the Defense Health Agency, supports research under the Military Medical Research and Development program (CFDA 12.420) to investigate the role of podocyte ceramide synthase 6 in focal segmental glomerulosclerosis (FSGS).

The primary awardee, the University of Texas Health Science Center at San Antonio, will conduct basic, translational, and clinical research to determine how genetic and toxin-induced FSGS affects ceramide production and expression of the ceramide synthase 6 enzyme in podocytes. The University of Miami and the University of Texas at El Paso are serving as sub-awardees, contributing specialized expertise in areas such as lipidomics, pathology, and statistical analysis to support the research.

The overall goal of this project is to advance the understanding of the molecular mechanisms underlying FSGS, with the potential to identify new therapeutic targets and improve treatment options for this kidney disease. The project will be carried out over a four-year period ending on March 31, 2028.

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