This Project Grant award from the Defense Health Agency under the Military Medical Research and Development Program (CFDA 12.420) provides $2,495,419.00 to The Trustees of the University of Pennsylvania (Penn) to develop a blood-based biomarker for detecting blood-brain barrier dysfunction in traumatic brain injury. The project aims to transform healthcare for service members and the public by developing innovative medical solutions for the battlefield through July 1, 2023 to June 30, 2027....
This $6,214,900 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program supports research on the role of genetic risk factors and immune response on neurovascular unit (NVU) function in post-traumatic brain injury (TBI) cognitive impairment. The primary awardee, the Scintillon Institute, a non-profit biomedical research organization in San Diego, California, will conduct this advanced scientific investigation over...
The U.S. Department of Defense's Military Medical Research and Development program (CFDA 12.420) awarded a $683,442 Project Grant on September 1, 2023 to The Trustees of the University of Pennsylvania to conduct a 3-year study on "Trajectories of Neuroimaging and Blood-Based Biomarkers After Remote Traumatic Brain Injury and Associations with Dementia Risk." The University of Pennsylvania will collaborate with Mayo Clinic on a sub-award to investigate longitudinal changes in brain...
The federal Project Grant award of $837,500.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) will fund research by The Feinstein Institutes for Medical Research on "OXYGEN CONSERVING REFLEX: A NOVEL MULTIMECHANISTIC THERAPEUTIC INTERVENTION FOR TBI." The research will investigate an innovative approach to address traumatic brain injury (TBI) by examining a novel oxygen conserving reflex. The award will support this...
The federal Project Grant award of $125,000.00 from the Office of Naval Research (ONR) under the Basic and Applied Scientific Research program (CFDA 12.300) supports computational modeling research on blast-induced traumatic brain injury (TBI) in an animal model. The award is for the period from March 11, 2025 to April 6, 2027 and is being performed by Robert Morris University (RMU), a private non-profit educational institution in Pennsylvania. The research focuses on developing human digital...
The federal Project Grant award in the amount of $1,999,996.00 was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program. The award supports research to identify diagnostic biomarkers of the cerebrovascular contributions to cognitive impairment in repeated blast concussion. The grant was awarded to Temple University-Of The Commonwealth System Of Higher Education, a prominent public research university in Philadelphia,...
This federal Project Grant award in the amount of $747,507 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports an evaluation of an engineered calpain activity nanosensor in a mouse model of traumatic brain injury (TBI) at the University of California, San Diego (UCSD). The objective of the research is to advance the development of innovative technologies for monitoring and assessing traumatic brain injuries,...
The Defense Health Agency awarded a $725,000 Project Grant to the University of Oklahoma Health Sciences Center to develop treatments for cognitive, motor, and sensory outcomes associated with mild traumatic brain injury and post-traumatic stress disorder. Funded through the Military Medical Research and Development program under the Cooperative Agreements and Other Transactions authority, this three-year award beginning April 15, 2023 will support research into modulating the NOP receptor...
The University of Oklahoma received a $2,273,306 federal Project Grant from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) to conduct research on "NEUROPEPTIDE MODULATION OF CEREBRAL BLOOD FLOW TO IMPROVE NEUROLOGICAL AND PSYCHOLOGICAL OUTCOMES FOLLOWING TBI IN THE PRESENCE AND ABSENCE OF TRAUMATIC STRESS". The 4-year grant, which began on Jul 1, 2023, aims to investigate medical solutions for traumatic brain injuries (TBI) and the impacts...
This Project Grant award of $613,585.00 from the Defense Health Agency (DHA) supports research by James Cook University's Australian Institute of Tropical Health and Medicine to develop point-of-injury intranasal drug therapies to reduce secondary injury and improve outcomes for individuals with traumatic brain injuries (TBIs) in civilian and military resource-limited environments. This research falls under the DHA's Military Medical Research and Development program (CFDA 12.420), which...