Project Grant HDTRA12510002

The American Type Culture Collection (ATCC) was awarded a $263,771 Project Grant from the Defense Threat Reduction Agency to conduct research titled "Genome-Wide Mapping (GWM) of Host Proteome: Pan Alphavirus Proteome Interactions for Discovery of Broad-Spectrum Countermeasures." The two-year project beginning October 12, 2021 aims to advance fundamental knowledge in scientific research combating weapons of mass destruction, as outlined in the agency's Scientific Research - Combating...

Federal Project Grant Award Summary New York University School of Medicine received a $466,125 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award funds research to elucidate the molecular mechanisms of orthopoxvirus entry, specifically examining the critical initial interactions between viral and human cellular proteins...

This Project Grant award of $392,500.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports a research program at Arizona State University (ASU) focused on improving the understanding of cross-species viral transmission from wild mammals to humans. The key objectives of the five-year project are to: 1) develop automated tools to curate and maintain up-to-date taxonomic data on mammal and virus species, 2) test...

This Project Grant award from the National Science Foundation provides $999,610 to The University of New Mexico to establish the Center for Emerging Pathogen Prediction and Integration (CEPPI) from September 1, 2022 through February 29, 2024. CEPPI will develop predictive models and workflows to strengthen global pathogen surveillance and pandemic prevention under the Biological Sciences (CFDA 47.074) program. Key products include establishing informatics baselines on pathogens and hosts from...

Federal Project Grant Award Summary Princeton University received a $239,355 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of August 18, 2025 and completion deadline of March 31, 2026. The research project, titled "Systematic Dissection of Viral Genetic Interactions and Mutations with CoExpreSEq," will deliver comprehensive analysis of lymphocytic...

Federal Project Grant Award Summary The National Science Foundation's Division of Integrative Organismal Systems awarded $335,268 to the University of Texas at Austin under the Biological Sciences program (CFDA 47.074) for a three-year project spanning August 1, 2025 through July 31, 2028. This research initiative investigates viral proteins (specifically viral dual-specificity phosphatase 11 or VDUSP11) that enable poxviruses to evade immune defenses across diverse host species—including...

The La Jolla Institute for Immunology received a $923,708 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 1, 2026, with a completion date of March 31, 2031. This five-year research initiative focuses on developing a therapeutic monoclonal antibody (MAB) cocktail targeting New World Arenaviruses (NWAs), including Machupo and Junin viruses, which cause hemorrhagic fever. The...

The Flavivirus and Alphavirus REVAMPP (FLARE) Center, funded by a $46,715,173 Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research), is developing and optimizing protein nanoparticle, virion-based, and mRNA vaccine platforms, as well as monoclonal antibody-based treatments to rapidly respond to emerging flaviviruses and alphaviruses with pandemic potential. The Center integrates the work of multiple...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the role of the Rift Valley Fever Virus (RVFV) non-structural small (NSS) protein in inhibiting the host autophagy pathway. The $128,052 award to Virginia Polytechnic Institute & State University will fund research to characterize the interaction between the NSS protein and the LC3 autophagy...

The Department of Agriculture Animal and Plant Health Inspection Service awarded Virginia Polytechnic Institute and State University $4,997,658 under the Plant and Animal Disease, Pest Control, and Animal Care federal grant program (CFDA 10.025) on June 1, 2023 for a project period ending May 31, 2025. The university will use mathematical modeling, field sampling, genomic surveillance, biochemical analysis, and immunological studies to expand knowledge of species susceptibility to SARS-CoV-2....