Developing selective p-catalysts for dehydrative transformations
Ended Project Grant Awarded Last action
- Award ID
- F32GM153091
- Recipient
-
Massachusetts Institute Of Technology UEI E2NYLCDML6V1
- Awarding agency
-
National Institute of General Medical Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $409,544
Award facts
- Assistance listing
- 93.859 Biomedical Research and Research Training
- Completion date
- Place of performance
- Cambridge, MA 02139, USA
Award details come from USAspending.gov.
Description
- Abstract
- This proposal will elucidate the various steric and electronic parameters of a p-catalyst necessary for enantioinduction in tandem amidation/amide functionalizations through deoxygenative p(III)/p(v) catalysis; an important transformation for the synthesis of biologically active compounds. This proposal will first examine p- catalyzed enantioselective amidations, followed by p-catalyzed enantioretentive amide functionalizations. Finally, these catalysts will be combined for a one-pot synthesis of enantioenriched secondary nitriles from racemic carboxylic acids, a moiety important to the pharmaceutical community. Overall, during this fellowship period i seek to gain expertise in inorganic main-group chemistry, including computational analyses and modern inorganic synthetic techniques. Such skills will complement my existing skillset, creating a strong foundation in catalyst design for my future career goals.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | -$32,820 | |
| Amendment | $1,284 | |
| Amendment | $76,756 | |
| Amendment | $76,756 | |
| Amendment | $4,784 | |
| Amendment | $4,784 | |
| Amendment | $69,500 | |
| Amendment | $0 | |
| Amendment | $69,500 | |
| Amendment | $69,500 | |
| Amendment | $0 | |
| Amendment | $69,500 | |
| Original award | $0 |
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Quick answers
Who received award F32GM153091?
F32GM153091 was awarded to Massachusetts Institute Of Technology by National Institute of General Medical Sciences (National Institutes of Health) on July 15, 2024.
How much is award F32GM153091 worth?
$409,544 has been obligated on F32GM153091.
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