This Project Grant award of $532,947 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund the development and validation of a unified, cloud-based data processing workflow and database called LC-BINBASE for high-resolution LC-MS/MS metabolomics and lipidomics data. The goal is to create a standardized and reproducible metabolomics data processing system that can be used across different laboratories and mass...
This Major Research Instrumentation Program award from the National Science Foundation will provide $580,393 to support the acquisition of a triple-quadrupole inductively coupled plasma mass spectrometer and three dedicated sample processing and introduction systems for the University of California, Santa Cruz's Institute of Marine Science Marine Analytical Laboratory. The laboratory will use the new instrumentation to enable multidisciplinary analytical work by faculty, researchers, and...
Christopher Newport University was awarded a $305,832 Project Grant from the National Science Foundation Office of Integrative Activities to acquire a liquid chromatography-quadrupole time-of-flight mass spectrometer. The award is part of the Integrative Activities program, which aims to enhance the competitiveness of the nation's research through activities that build STEM capacity and broaden participation in research and education. The mass spectrometer will support multidisciplinary research...
This Project Grant award, totaling $620,000.00, was provided by the U.S. Geological Survey (USGS) under the Assistance to State Water Resources Research Institutes program (CFDA 15.805). The purpose of the award is to determine the effects of per- and polyfluoroalkyl substances (PFAS) on microbiome health and neurotoxicity in bluegill, an economically and ecologically important fish species in the Great Lakes region. The key research activities include: 1) characterizing PFAS bioaccumulation and...
This $406,843 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) supports research at the University of South Florida (USF) to investigate the role of G protein-coupled receptors (GPCRs) in the bioluminescence signaling of the red tide dinoflagellate Lingulodinium polyedra. The key objectives are to: 1) evaluate the mRNA levels of a target GPCR candidate (RC3) and its effectors using RT-qPCR and...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $459,353 to the University of Toledo to conduct research on the discovery and characterization of novel cyanotoxins produced during harmful cyanobacterial blooms. The key objectives are to: 1) optimize high-performance liquid chromatography (HPLC) with native fluorescence detection and mass spectrometry (MS/MS) for structural...
This federal Project Grant award, valued at $476,385.00 and funded by the National Science Foundation's (NSF) Division of Chemistry, supports a collaborative research project between Professor Michael Marty's team at the University of Arizona and industrial partners at Genentech, Inc. The project aims to develop new computational algorithms and experimental methods for improved analysis of complex mass spectrometry data, particularly focused on enabling more widespread use of intact mass...
This $553,708 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, aims to advance the development of a community-led Zebrafish Toxicology Phenotype Atlas. The key products and services to be delivered include: Designing and deploying a standardized Toxicophenotype Data Model to improve data compatibility across zebrafish toxicology studies and domains. Creating a Toxicophenotype Annotation Toolkit to...
This $470,000 Project Grant from the National Science Foundation (NSF) Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports the development of new analytical detection and processing tools for the characterization of complex mixtures, with a focus on dissolved organic matter (DOM). Researchers at Florida International University are creating a platform that combines ion mobility spectrometry and ultra-high-resolution Fourier transform ion...
This $949,116 Project Grant awarded by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a Thermo Fisher Scientific Orbitrap IQ-X mass spectrometer system with a Vanquish Flex UHPLC system at the University of South Florida (USF). This cutting-edge analytical instrumentation will establish a unique omics capability at USF to support detailed, high-resolution structural analysis of low-level small molecules in complex...