Project Grant F31AI203218
- The National Institute of Allergy and Infectious Diseases (NIAID), part of the Department of Health and Human Services National Institutes of Health, awarded $149,190 to the University of Massachusetts Medical School on December 17, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project grant (F31AI191745) to investigate hemagglutinin-mediated molecular mechanisms of avian influenza A virus host tropism. The research examines how the hemagglutinin (HA)...
- The National Institute of Allergy and Infectious Diseases awarded Brown University $100,228 on February 17, 2027, to support pre-doctoral research training under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds development and application of long-read sequencing technologies to resolve the evolutionary origins and dissemination of artemisinin resistance in African Plasmodium falciparum malaria. The fellow will develop a validated multiplex long-range PCR and...
- The National Institute of Allergy and Infectious Diseases awarded Duke University $695,041 on August 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate mechanisms underlying combination adjuvant-driven improvement of influenza vaccine responses. The research defines the innate immune signatures and adaptive immune responses elicited by existing and novel combination adjuvants as they relate to driving immune responses directed against influenza virus...
- The National Institute of Allergy and Infectious Diseases awarded Loyola University of Chicago Health Sciences Campus $462,000 on August 18, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on mechanistic understanding of influenza virus inhibition by non-canonical ISG15. The research examines how alternative splicing of the interferon-stimulated gene ISG15 produces novel transcript isoforms that inhibit influenza virus replication. The project...
- The National Institute of Allergy and Infectious Diseases awarded the University of Rhode Island $2,334,838 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a multiantigen-based universal influenza vaccine using a versatile virus-like particle platform. The research optimizes flagellin-displayed hepatitis B core virus-like particles (FH VLPs) as a vaccine platform and develops M2E/HA stem and NP/M1 universal influenza vaccines. The work...
- The National Institute of Allergy and Infectious Diseases awarded $721,365 to the University of California Irvine on April 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a single-dose influenza vaccine platform that extends immune response breadth against viral variants. The funded research combines nanoparticles presenting H5 hemagglutinin antigen with thermo-responsive polymer depots that release antigen slowly, extending exposure time to elicit...
- The National Institute of Allergy and Infectious Diseases awarded the University of Wisconsin - Madison $414,861 under Project Grant R21AI195857 on September 1, 2026, through the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds research into the evolutionary pathways by which influenza virus variants acquire antiviral resistance. The investigator will use engineered viral libraries carrying random nucleotide barcodes on the PA segment of the influenza genome to...
- The National Institute of Allergy and Infectious Diseases awarded the University of Missouri System $3,987,706 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate immune mechanisms shaping airborne influenza transmission through an integrated program combining swine and human studies with multiscale computational modeling. The research addresses the mechanistic gap in understanding how host immunity and environmental conditions govern...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $2.959 million on August 25, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Michigan Influenza Transmission Research Center's observational studies of human influenza transmission. The award funds three coordinated research projects examining influenza transmission through the epidemiologic triangle framework of pathogen, host, and...
- The National Institute of Allergy and Infectious Diseases awarded the University of Washington $182,422 on April 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support a Research Career Development Award (K01) training and research program on influenza vaccine optimization. The award funds a five-year project running through March 31, 2031, based in Seattle, Washington. The principal investigator will dedicate 75 percent effort to developing methodological...
The National Institute of Allergy and Infectious Diseases awarded Brown University $100,228 on February 13, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to assess climate and spatial drivers of influenza dynamics across temperate and tropical settings. The recipient will develop a multinational dataset integrating spatially- and temporally-resolved influenza surveillance data, environmental variables, and human mobility indicators to evaluate how weather factors shape influenza activity across global sites, estimate influenza transmission as a function of specific humidity and temperature, and quantify the relative contributions of environmental and human mobility factors in shaping influenza epidemics in the United States. The study employs parametric and non-parametric approaches including infectious disease modeling, statistical analysis, and machine learning methods to address unexplained variability in subnational outbreak patterns and improve anticipation of influenza activity for strategic resource allocation and public health preparedness. Performance occurs in Providence, Rhode Island, with work completion by August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/13/26 | ||
| Not listed | $50.1k | 8/13/26 |