Project Grant DP2MH136393
- This $1,330,000 Project Grant award from the National Institutes of Health's Trans-NIH Research Support program (CFDA 93.310) supports research conducted by the Salk Institute for Biological Studies in La Jolla, CA. The goal of the research is to discover how the brain's cortical activity and synaptic plasticity create the temporal context that allows us to integrate and retain new information over minutes and hours. The project will investigate the role of cortical traveling waves in this...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
- This federal Project Grant award, valued at $358,313.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award will fund a 5-year research study at Drexel University to investigate how prior knowledge shapes the learning and long-term consolidation of new memories in healthy human adults. The research will utilize functional neuroimaging (fMRI) and...
- This federal Project Grant award was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco (UCSF). The $781,119 award, with a performance period from March 1, 2025 to December 31, 2029, will support research to understand the neural population dynamics and circuit mechanisms in the ventral hippocampus that represent conditioned and unconditioned stimuli during...
- The National Institute of Neurological Disorders and Stroke has awarded Albert Einstein College of Medicine a $2,923,021 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, titled "Integrative Analysis of Adaptive Information Processing and Learning-Dependent Circuit Reorganization in the Auditory System," will fund research to investigate the neural mechanisms underlying auditory...
- This $223,176 federal project grant awarded on January 28, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research at Stanford University to better understand the neural circuits and computations governing flexible spatial processing in the medial entorhinal cortex (MEC). The research leverages advanced high-density electrophysiology and 3D video...
- This federal Project Grant award, valued at $216,689.00 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research aimed at measuring the effective connectivity between excitatory and inhibitory neurons in the brain to reveal the underlying connectivity motifs and computations that contribute to decision-making. The research, to be conducted by...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $381,375.00 to New York University to develop genetic strategies to study a novel disinhibitory system in the cortex. Specifically, the project aims to gain a detailed understanding of how top-down and bottom-up signals are integrated in the superficial...
- This $274,218.64 Project Grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke to Brandeis University will support research into the mechanisms underlying exosome release from neurons. The grant aims to determine how exosomes are generated from the endosomal system in neurons and explore neuronal exosome and endosome biology in an animal model. The grantee will manipulate the ESCRT and MUNC13-4/RAB11 pathways to investigate endosomal dynamics...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $673,581 to New York University (NYU) to study the dynamics of the cortical-hippocampal circuit and its role in statistical learning. The goal is to build a mechanistic neurobiological circuit theory of statistical learning, which is a fundamental cognitive process enabling the...
The federal Project Grant award in the amount of $4,245,501.00 from the National Institutes of Health (NIH) under the Trans-NIH Research Support (CFDA 93.310) program supports research at Brandeis University to unravel the synaptic and circuit mechanisms underlying a plasticity-driving instructive signal in the brain. The project aims to determine how the medial entorhinal cortex layer 3 (MEC3) produces a context-specific target signal that drives behavioral timescale synaptic plasticity (BTSP) in the hippocampal CA1 region, thereby directing the formation of learning-related neural representations. To achieve this, the researchers will use extracellular recordings, in vivo whole-cell recordings, and optogenetics to investigate the flow of information and single-cell computations within the MEC network during a flexible spatial memory task in awake mice. The findings could provide fundamental insights into the neural mechanisms of learning, with broad implications for understanding complex brain functions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 8/22/23 | ||
| Not listed | $1.4m | 8/17/23 | ||
| Not listed | $1.4m | 8/17/23 |