Project Grant 83332701

This $637,553 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, funds research to assess the toxicity, uptake, and biodistribution of environmentally relevant micro-nanoplastics (MNPs). The 5-year project, conducted by Rutgers University, will develop and characterize various MNP materials, including aged MNPs, to examine their interaction with intestinal epithelial cells, the role of...

This $900,804 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports the development and validation of an integrated microphysiological screening platform (MPS) with "virtual human" models to assess chemical toxicity and variability in human responses. The key objectives are to create an MPS platform that can elucidate inter-donor variabilities in mitochondrial toxicity and...

This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $353,941 to The Research Foundation for the State University of New York, doing business as Stony Brook University, to support research on understanding and controlling the physical adhesion and aggregation of nanomaterials in liquid environments. The key objectives are to develop a predictive model for nanoparticle adhesion by considering the effects of solvent-induced...

This $191,801 National Science Foundation Project Grant under the Integrative Activities program will support research into the properties and toxicity of microplastics and nanoplastics through a combination of experimental and computational methods. Professor B. Rasulev of North Dakota State University will lead an interdisciplinary collaboration with Rutgers University to characterize micro- and nanoplastic materials experimentally and computationally. Structure-toxicity analysis and...

This federal Project Grant award of $428,387 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research to develop novel procedures for synthesizing environmentally relevant micro- and nanoplastics. The goal is to investigate how the physicochemical properties of these nanoplastics, including their interactions with environmental contaminants and biomolecules, may influence their toxicological consequences. This...

This $157,667 Project Grant awarded by the Environmental Protection Agency (EPA) under the Science to Achieve Results (STAR) Research Program (CFDA 66.509) aims to develop a predicted reaction network using experimental and computational data. The purpose is to describe the environmental lifecycle of persistent biological transformation products (TPs) of chemicals in order to improve the chemical products manufacturing industry and understanding of how chemicals act at different stages of...

This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $370,980 to Tarleton State University to conduct a 3-year meta-transcriptomic assessment of the potential health impacts of chronic respiratory exposure to cobalt-based nanomaterials. The project will utilize advanced 3D lung models to evaluate the fate, translocation, and toxicology of cobalt and cobalt oxide nanomaterials, with a focus on...

The National Institute of Environmental Health Sciences (NIEHS) awarded a $546,350 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to The Research Foundation For The State University Of New York (RF SUNY) to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The key objectives of this 4.8-year research project are to: 1) characterize the mechanisms by which PFAS are taken up and accumulated in neurons, 2)...

This $500,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program aims to develop a novel human stem cell-based microfluidic developmental toxicology platform. The University of Michigan will receive funding from September 2022 to August 2024 to conduct technological development of a repeatable, controllable, high-throughput microfluidic system for generating three-dimensional multicellular organoid models for toxicity testing. The platform seeks...

This three-year Project Grant from the United States Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program will fund $608,676 to the University of Florida's Division of Sponsored Research to investigate the impacts of nanomaterials on soil and water microbiomes and pathogen persistence in agrifood systems. The University will synthesize and characterize twenty types of monodisperse nanomaterials and study...