Project Grant 2625575
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded the University of Connecticut $200,000 on October 1, 2026, under the Engineering program (CFDA 47.041) to develop wearable electrochemical sensors for continuous heart failure monitoring. The project will create an aptamer-based electrochemical platform combining molecular-recognition engineering, electrically controlled sensing, and wearable microneedle technology to measure N-terminal pro-B-type...
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded $200,000 to the University of Houston on October 1, 2026, for collaborative research developing FBEP-enabled electrochemical sensors for heart failure monitoring under the Engineering program (CFDA 47.041). The research develops a wearable sensing approach for continuous monitoring of N-terminal pro-B-type natriuretic peptide in skin interstitial fluid as an alternative to intermittent blood draws...
- The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Cincinnati Sponsored Research Services Division $398,400 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop chemically-modified aptamer electrochemical sensors for ultra-sensitive biomonitoring. The research advances continuous biochemical monitoring technology to detect biomarkers at picomolar-to-nanomolar...
- This Project Grant award for $299,712 from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the development of electrochemical aptamer-based (E-AB) sensors for the rapid and accurate detection of multiple cardiovascular disease (CVD) biomarkers. The University of South Carolina, with mentorship from collaborators at the University of Cincinnati, will design and characterize these multiplexed E-AB sensors to enable early diagnosis of CVDs, which are...
- The National Science Foundation awarded a $294,100 project grant to the University of Kansas Medical Center Research Institute, Inc. to support research titled "EAGER: ENGINEERING OPTICAL NANOBIOSENSORS FOR DETECTION OF CORONAVIRUS PROTEASES" under the NSF Engineering program (CFDA 47.041). The grant funding will support the development of optical nanobiosensors for detecting coronavirus proteases from March 15, 2021 through October 31, 2022. The NSF Directorate for Engineering seeks...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Santa Barbara $582,137 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop electrochemical aptamer-based sensors for long-duration, real-time molecular measurements in living tissue. The research aims to extend the in vivo operational lifespan of electrochemical aptamer-based sensors beyond their...
- The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to the University of Missouri System to develop six-lead, wearable heart monitors using innovative, multifunctional, porous, soft materials. The project aims to enhance wearable heart monitors for improved cardiac health management by addressing current limitations in ambulatory ECG monitoring, such as motion-induced artifacts and limited...
- This $400,000 Project Grant from the National Science Foundation's Division of Electrical, Communications and Cyber Systems, under the Engineering (47.041) federal grant program, will fund research at Georgia Tech Research Corporation to advance implantable bioelectronics for continuous monitoring of vascular health. Specifically, the grant will support understanding of printing soft microstructures for enhanced sensor sensitivity, study of passive wireless sensing principles and 3D...
- This $200,000 Project Grant awarded by the National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems under CFDA 47.041 (Engineering) aims to develop and implement a novel testing platform to evaluate the accuracy of wearable photoplethysmography-based blood pressure monitoring devices. The University of Maryland, College Park will construct a bench flow phantom that simulates physiologically relevant blood pressure, blood flow, anatomical, and optical...
The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded the University of Kansas Center For Research Inc. $200,000 on October 1, 2026, under the Engineering program (CFDA 47.041) to develop electrochemical sensors for continuous heart failure monitoring. The research will engineer an aptamer-based electrochemical platform combining molecular-recognition engineering, electrically controlled sensing using fast biphasic electric pulse waveforms, and wearable microneedle technology to detect N-terminal pro-B-type natriuretic peptide in skin interstitial fluid. Current heart failure monitoring relies on intermittent blood draws providing isolated diagnostic snapshots; this wearable sensing approach aims to enable higher-frequency NT-proBNP measurements that could reveal rising, falling, or rebound trajectories and support earlier recognition of worsening disease or treatment response. The project has three interdependent objectives: developing and optimizing NT-proBNP-binding aptamers with high affinity, selectivity, and stability in biofluids at physiological temperature; determining how fast biphasic electric pulse waveform parameters and electrochemical readout conditions control signal generation, interface recovery, and sensing bandwidth; and additional research elements on electrochemical interfaces and sensor validation. The project will train students in chemistry, electrochemistry, biointerfaces, and biomedical engineering, and incorporate research concepts and results into undergraduate and graduate course modules and educational and public outreach activities on wearable biosensors and heart-health monitoring. The period of performance runs from October 1, 2026 through September 30, 2029, with work performed in Lawrence, Kansas.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.0k | 8/5/26 |