Project Grant 2617659
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $262,753 to Smith College on September 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate spinal neuron diversity and the evolution of novel motor behavior in frogs. The research examines how the nervous system evolves to produce new and complex behaviors by studying foot-flagging frogs that perform elaborate hind-limb communication displays. The project identifies genes and specific...
- The University of Utah will receive $492,516 from the National Science Foundation Division of Molecular and Cellular Biosciences under a three-year Project Grant award titled "Role of Electric Fields and a Dynamic Local Environment in Protein-RNA Molecular Recognition." The grant funds basic research from August 1, 2021 to July 31, 2024 to advance understanding of major problems in the biological sciences by investigating the role of electric fields and the local molecular...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of Utah $998,752 on September 1, 2026, under the Biological Sciences program (CFDA 47.074) to define spatiotemporal regulation and integration of phytochrome B signaling complexes in plant cells. The research identifies molecular components of cellular signaling complexes under varying conditions of light, temperature, and amino acid availability to determine how plants regulate growth and...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded The University of Iowa $1.232 million under the Biological Sciences program (CFDA 47.074) on July 1, 2026, to investigate the molecular mechanisms and regulation of motor proteins that drive active mechanosensation in insects. The research focuses on understanding how motor proteins generate active antennal oscillations in fruit flies and mosquitoes, which amplify sensitivity to sound signals through...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1.8 million to the University of California, San Diego on August 1, 2026, under the Biological Sciences program (CFDA 47.074) to probe connectivity update rules in biological neural networks in vivo. The research will develop an all-optical approach combining two-photon calcium imaging, single-cell holographic optogenetic stimulation, and functional connectivity mapping to measure and experimentally induce...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded North Carolina State University $1.5 million on July 15, 2026, for research on neural recognition of acoustic courtship songs in Drosophila under the Biological Sciences program (CFDA 47.074). The project investigates how individual neurons recognize specific sounds by studying sound-sensitive neurons in fruit flies as a model system. Researchers will use genetic tools to record and control neuron activity...
- The National Science Foundation Division of Emerging Frontiers awarded Utah State University $249,955 on June 1, 2026, under the Biological Sciences program (CFDA 47.074) to develop standardized computational workflows for modeling and inference of RNA strand-exchange circuits. The project will create a machine-readable computational workflow that uses experimental data and artificial intelligence to improve mechanistic models of engineered biological systems. Using genetically encoded RNA...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,197,230 to The Trustees of Columbia University in the City of New York on June 1, 2026, under the Biological Sciences program (CFDA 47.074). The award funds research investigating the neural basis for social prediction in weakly electric mormyrid fish—specifically how the nervous system learns to predict sensory consequences of actions produced by other individuals and which cells and circuits execute...
- The National Science Foundation Division of Computing and Communication Foundations awarded the University of Oregon $897,184 on September 1, 2026, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop factorial state-space models that disentangle multiscale neural dynamics in brain-wide recordings. The research addresses the challenge of separating overlapping brain processes occurring simultaneously across timescales ranging from milliseconds to minutes in...
- The National Science Foundation awarded a $138,000 Project Grant to support research under the Biological Sciences federal grant program (CFDA 47.074) from July 1, 2021 to June 30, 2023. The grant funds postdoctoral research examining the neural integration of acoustic signals across reproductive states in female birds. Consistent with the program's goal of advancing the biological sciences, this award will enhance understanding of how the brain processes sounds differently during breeding...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of Utah $1.587 million on July 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate mechanisms of fast rhythm generation in vertebrate neural circuits. The research team will use high-density brain recording technologies and AI-assisted modeling to study how the African clawed frog brain generates fast motor rhythms with millisecond precision, using an isolated brain preparation that produces fictive vocal calls for hours. The work aims to define neural mechanisms driving fast vertebrate motor patterns—specifically the ~60-hertz stereotyped activity of the vocal central pattern generator—through simultaneous electrophysiology, targeted pharmacological perturbations, and population-level analyses. The investigators hypothesize that a stereotyped motoneuron recruitment sequence drives call amplitude, while spike synchrony mechanisms control frequency and timing. The project runs through June 30, 2029, with place of performance at Salt Lake City, Utah. Beyond fundamental neuroscience contributions, the work will advance AI tools for analyzing complex biological signals and inform future approaches to understanding neurological and psychiatric disorders linked to disrupted fast brain rhythms. The award includes STEM education and outreach activities in prisons, K-12 classrooms, and community programs, alongside research training for students at multiple career stages.
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