Project Grant 2604271
- Federal Grant Award Summary Singular Immune, Inc. received a $304,909 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) effective July 1, 2026, with a completion date of June 30, 2027. The award funds development of a novel protein-based platform that enables Chimeric Antigen Receptor (CAR) generation in vivo without genetic modification of cells. Rather than inserting...
- This SBIR Phase I award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $273,550 to Biocognon LLC for the development of a combinatorial platform to discover improved molecular recognition components for use in therapeutic and diagnostic antibodies. The project aims to utilize synthetic biology, next-generation DNA sequencing, and computational biology to efficiently generate and screen libraries of antibody...
- Federal Project Grant Award Summary Yolo Immune Inc. received a $304,665 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) on October 1, 2025, with completion scheduled for September 30, 2026. The company is developing a novel immunotherapy drug designed to selectively deplete immunoglobulin G4 (IgG4) autoantibodies, a specific antibody subclass implicated in multiple...
- Federal Grant Award Summary Immuno Nano Med, Inc. received a $305,000 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084), effective October 1, 2025, with completion targeted for September 30, 2026. The award supports development and feasibility demonstration of a novel room-temperature-stable, dry-powder inhalable influenza vaccine utilizing a scalable manufacturing process....
- Federal Grant Award Summary Nitro Biosciences Inc. received a $304,438 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) effective October 1, 2025, with a completion date of September 30, 2026. The award supports development of an innovative vaccine platform utilizing engineered antigens containing chemically modified amino acids to overcome immune imprinting—a critical...
- Federal Grant Award Summary Primary Bioscience, Inc. received a $305,000 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) effective July 15, 2025, with a completion date of June 30, 2026. The company is developing an ultra-sensitive biosensor capable of single-molecule protein analysis and sequencing. The technology integrates a nanopatterned chip with a proprietary amino acid and...
- Federal Grant Award Summary Ivsonance Biomedical Inc. received a $305,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) effective October 1, 2025, through September 30, 2026. The awardee, based in Ithaca, New York, is developing a semi-automated acoustic tweezer system that uses modulated sound waves to provide contactless micromanipulation of delicate biological materials...
- Federal Grant Award Summary Foli Bio Inc. received a $305,000 Phase I Small Business Innovation Research (SBIR) award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to develop a high-throughput fecal exfoliome analyzing platform for clinical drug development. The award, initiated October 1, 2025, with completion targeted for September 30, 2026, funds the advancement of a stool-based diagnostic technology that captures and...
- Federal Project Grant Award Summary Synlibris, Inc. received a $304,957 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation's Directorate for Technology, Innovation, and Partnerships (CFDA 47.084) effective July 1, 2026, through June 30, 2027. The project develops a continuous evolution platform technology designed to accelerate the discovery of genetic solutions for high-yield protein biomanufacturing. The core innovation utilizes an orthogonal DNA...
- Federal Grant Award Summary The National Science Foundation (NSF) awarded Piezo Therapeutics, Inc. a $304,742 Project Grant under the Technology, Innovation, and Partnerships program (CFDA 47.084) for a Phase I Small Business Innovation Research (SBIR) project running from October 1, 2025 through September 30, 2026. The awardee will develop and validate a novel intradermal vaccine delivery platform that eliminates the need for lipid nanoparticles (LNPs) by utilizing electroporation technology....
Ichor Biologics LLC received a $305,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation's Directorate for Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) for the period July 1, 2026 through June 30, 2027. The company will develop an integrated technology platform designed to identify and measure disease-specific immune responses, specifically targeting the challenge of linking antigen-specific B cell responses to functional antibody activity. The proposed system will selectively activate and expand antigen-specific B cells through controlled antigen presentation and programmable co-stimulation, addressing a significant gap in existing immunological tools that either measure antibody binding without identifying producing cells or sequence immune cells without determining their antigenic targets. This innovation is intended to accelerate drug discovery and clinical decision-making by enabling researchers to distinguish protective from harmful immune responses across individuals and disease conditions. The technology platform has commercial applications in vaccine development, therapeutic discovery, and personalized medicine approaches for treating chronic and infectious diseases, while addressing an unmet market need for improved immune monitoring tools in the biotechnology and pharmaceutical sectors.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 6/25/26 |