Project Grant 2603372

The National Science Foundation Division of Chemistry awarded The Trustees of Columbia University in the City of New York $480,000 on August 15, 2026, for collaborative research on cyclopropenimine-mediated organo-carbonation polymerizations under the Mathematical and Physical Sciences program (CFDA 47.049).

The research explores synthesis of polymers incorporating carbon dioxide into their core structure, employing computational techniques and artificial intelligence methods to guide selection of molecular building blocks and reaction conditions. A central focus is development of all-organic catalysts and reagents to avoid metal-based catalysts that are difficult to remove from final products. The research team will employ a feedback loop strategy where calculations and AI-based methods are used in conjunction with experimental findings to refine predictive capabilities for AI-driven discovery. Expected outcomes target advancement of polyurethane and polycarbonate manufacturing, particularly for advanced manufacturing and consumer product applications, and development of new chemistry-focused AI models enabling unprecedented synthetic methods to access new polymer classes.

The project includes workforce development activities centered on evidence-based mentorship, partnership, and inclusivity, with outreach spanning early classroom experiences through early-career professional development.

Performance runs through July 31, 2029, at Columbia University's location in New York, New York.