Project Grant 2601586
- Federal Grant Award Summary Lehigh University received a $300,000 CAREER (Faculty Early Career Development) award from the National Science Foundation's Engineering program (CFDA 47.041), effective February 15, 2026, through December 31, 2029. The project focuses on developing a novel diagnostic methodology to detect critical congenital heart defects (CCHDs) in newborns by analyzing chest surface vibrations recorded through seismocardiography (SCG) and gyrocardiography (GCG). The research aims...
- The National Science Foundation (NSF) Engineering program awarded a $695,746 CAREER grant to The Washington University's Office of Sponsored Research Services Division to support research aimed at understanding how to grow more mature heart muscle from induced pluripotent stem cells (iPSCs) in the laboratory. The research project will investigate how combining mechanical loading and changes in energy sources can enhance the electrical maturation of iPSC-derived cardiomyocytes to better predict...
- The National Science Foundation awarded a $279,606 Project Grant to the University of California Irvine under the Engineering federal grant program (CFDA 47.041). The grant supports collaborative research to develop multiscale computational models characterizing how heart muscle cells adapt mechanically to changes in load conditions. Through experimental measurement and multi-scale modeling, the university researchers will elucidate the acute functional response and long-term remodeling response...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $615,000 Faculty Early Career Development (CAREER) Program Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation (CFDA 47.041 - Engineering) awarded on June 1, 2026, with a completion date of May 31, 2031. This award funds fundamental research to advance understanding of cellular biomechanics and mechanobiology by developing novel technologies and...
- This CAREER (Faculty Early Career Development) Project Grant awarded by the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074) supports fundamental research investigating robustness and recovery mechanisms during organ formation, with a specific focus on cardiac development. The award of $500,000, granted to The University of Mississippi on September 15, 2025, with completion targeted for August 31, 2030, will...
- Federal Grant Award Summary The University of Michigan received a $219,999 Faculty Early Career Development (CAREER) Project Grant award dated December 15, 2025, from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041). The project, which extends through December 31, 2027, delivers research and development products focused on engineering instructive microenvironments to guide single stem cell...
- Federal Project Grant Award Summary San Diego State University Research Foundation received a $115,117 Project Grant award dated August 15, 2025, from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041). This collaborative research project delivers fundamental scientific research and computational modeling services focused on characterizing right ventricle viscoelasticity changes under acute stress and...
- This $262,138 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research at the University of Houston to investigate the mechanisms of cardiac fibrosis, a type of scarring in the heart that leads to impaired function. The key objectives are to: 1) determine the role of the endothelial-mesenchymal transition in cardiac fibrosis, and 2) develop a 3D cardiac fibrosis model to study tissue remodeling. The research will leverage a...
- Federal Grant Award Summary Emory University received a $500,001 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective June 1, 2026 through May 31, 2031. The award funds development of high-precision phototoxic subtractive engineering technologies for tissue reshaping and regenerative medicine applications. The primary deliverables...
- The National Science Foundation awarded a $450,000 Project Grant to the George Washington University under the Engineering federal grant program (CFDA 47.041) to develop scalable heart-on-a-chip platforms. Over a three-year period from April 2022 through March 2025, the University will create automated systems integrating human heart slice culture components with sensor and actuator arrays. This will enable continuous on-chip multiparametric analysis of human cardiac physiology at the cellular...
The National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation awarded the University of New Mexico a CAREER (Faculty Early Career Development) grant totaling $517,390 beginning October 1, 2025, with completion targeted for July 31, 2027. Under the Engineering program (CFDA 47.041), this project grant supports fundamental research to develop engineered adult heart tissue capable of replacing damaged heart muscle following cardiac events. The research will leverage induced pluripotent stem cells derived from patients' own cells to create personalized heart tissues by investigating how multiscale biophysical cues—including stiffness, viscoelasticity, and three-dimensional geometric confinement—influence cardiomyocyte maturation at the microscale and mesoscale levels. Beyond the core research objectives, the award includes a complementary education component designed to promote equity in engineering education through curriculum innovation and expanded access to engineering programs for populations historically underrepresented in the field. The project will establish scalable K-12 outreach initiatives alongside the research platform development, integrating educational advancement with the scientific investigation of biophysical signal mechanisms for heart tissue engineering.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $517.4k | 12/4/25 |