Project Grant 2545668
- Federal Grant Award Summary Primary Bioscience, Inc. received a $305,000 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) effective July 15, 2025, with a completion date of June 30, 2026. The company is developing an ultra-sensitive biosensor capable of single-molecule protein analysis and sequencing. The technology integrates a nanopatterned chip with a proprietary amino acid and...
- Federal Project Grant Summary Endura Therapeutics Inc. received a $303,445 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) on May 15, 2025, with completion targeted for January 31, 2026. The award funds development of a next-generation sequencing-based platform designed to discover and screen small molecule drugs that target RNA. The primary deliverables include establishing...
- Federal Project Grant Award Summary Award Overview: The National Science Foundation (NSF) awarded $305,000 under its Technology, Innovation, and Partnerships program (CFDA 47.084) to Roke Biotechnologies LLC for a Small Business Technology Transfer (STTR) Phase I project commencing July 1, 2026 and concluding June 30, 2027. The project focuses on developing a low-cost manufacturing platform for agricultural peptides using semi-continuous fermentation technology, performed at the awardee's...
- Federal Project Grant Summary Phase, Inc. received a $304,761 National Science Foundation (NSF) Small Business Technology Transfer (STTR) Phase I award under the Technology, Innovation, and Partnerships program (CFDA 47.084) effective June 1, 2026, through May 31, 2027. The project advances high-resolution 3D printing technology for polydimethylsiloxane (PDMS) microfluidic devices—commonly referred to as "labs on a chip"—which are essential tools for disease research, drug testing, and...
- Federal Project Grant Award Summary The National Science Foundation's Directorate for Technology, Innovation, and Partnerships (TIP) awarded $305,000 to a small business under the SBIR Phase I program (CFDA 47.084) to develop a novel gene therapy platform that overcomes the cargo size limitations of adeno-associated virus (AAV) delivery systems. The project, initiated July 1, 2026 with completion targeted for December 31, 2027, focuses on designing and validating a scalable platform to deliver...
- Federal Grant Award Summary Biostorex LLC received a $303,998 Small Business Technology Transfer (STTR) Phase I Project Grant from the National Science Foundation (NSF) Directorate for Technology, Innovation, and Partnerships (CFDA 47.084), awarded January 1, 2027, with completion anticipated by December 31, 2027. The project focuses on developing novel enzymatic DNA-synthesis technology for scalable and sustainable long-term digital data storage. The research aims to engineer a light-responsive...
- The National Science Foundation (NSF) awarded a $274,980 SBIR Phase I Project Grant to Cisterna Biologics, Inc. to develop a novel platform for cost-efficient mRNA production in yeast. The project aims to transform yeast cells into efficient mRNA factories and utilize advanced chromatographic techniques for purification, with the goal of reducing mRNA manufacturing costs by 90% compared to current in vitro transcription methods. Key technical objectives include demonstrating stable mRNA fusion...
- Federal Project Grant Award Summary Award Details: Plexymer, Inc. received a $305,000 Project Grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) beginning July 1, 2025, with completion targeted for June 30, 2026. The award supports SBIR Phase I research conducted in North Plainfield, New Jersey. Products and Services: Under this award, Plexymer will develop an artificial intelligence (AI)-driven platform for accelerated...
- Federal Grant Award Summary Peptiforge, Inc. received a $306,872 Phase 1 Small Business Innovation Research (SBIR) pre-commercialization grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. The company is developing a proprietary platform technology designed to accelerate the discovery and development of protein binders—proteins that selectively bind...
- Federal Project Grant Award Summary Vivid Bioinnovations, PBC (operating as Fluid Discovery, Inc.) received a $306,872 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2025 through July 31, 2026. The award supports development of a commercial prototype for an ultrahigh-throughput biocatalyst evolution platform that combines precision nanoliter fluid handling, label-free...
Federal Project Grant Award Summary Synlibris, Inc. received a $304,957 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation's Directorate for Technology, Innovation, and Partnerships (CFDA 47.084) effective July 1, 2026, through June 30, 2027. The project develops a continuous evolution platform technology designed to accelerate the discovery of genetic solutions for high-yield protein biomanufacturing. The core innovation utilizes an orthogonal DNA replication system that enables helper genes to mutate at extremely high rates without damaging host cell genomes, thereby enabling production of complex proteins that are currently difficult or toxic to manufacture at scale. The deliverables from this Phase I award include validation of three proprietary selection systems that couple cell survival to protein secretion and stability, as well as engineered yeast strains capable of tolerating and secreting benchmark proteins that present existing manufacturing challenges. The project will produce novel genetic variants that substantially improve protein yield and demonstrate the transferability of these variants to common production organisms, establishing a generalizable workflow for rapid strain engineering. These research outputs aim to reduce biologic drug manufacturing costs, enable novel industrial enzymes, and strengthen U.S. biomanufacturing competitiveness.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 6/17/26 |