Project Grant 2544766

Miami University received a $763,232 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences (Biological Sciences program, CFDA 47.074) awarded June 1, 2026, with completion targeted for May 31, 2029. The primary deliverable is fundamental research investigating the principles governing gene regulatory network evolution, utilizing beetle wing morphology as a model system to determine whether evolutionary changes in gene interactions follow predictable rules or inherent constraints. The research will generate novel scientific insights into how organisms develop new body structures by reusing and reconfiguring existing genes rather than creating entirely new genetic material.

Beyond core research outputs, the grant integrates education and outreach services through multiple mechanisms: a student-driven gene annotation initiative conducted in the teaching laboratory where undergraduate students perform original genetic experiments and contribute findings to a publicly accessible database; and science outreach initiatives designed to engage and recruit individuals with disabilities into scientific careers. The project's anticipated intellectual products have applicability to biotechnology and bioinspired engineering, with potential relevance to synthetic gene circuit design, adaptive biological systems development, medical diagnostics, environmental remediation, and bioproduction optimization.