Project Grant 2543698
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $504,681 to Tulane University for the CAREER project "From Energy Flow to Function: A Biophysical Framework for Rational Enzyme Evolution," effective June 1, 2026 through May 31, 2031 (CFDA 47.074, Biological Sciences program). The primary research product consists of a quantitative biophysical framework that elucidates the relationship between intramolecular...
- Federal Grant Award Summary Tulane University received a $275,000 Project Grant from the National Science Foundation's Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049) effective April 1, 2026, through March 31, 2029. This collaborative research initiative focuses on elucidating the structure and function of direct delivery peptides (DDPs), specifically investigating how these peptides cross cell membranes and deliver cargo molecules more...
- Federal Project Grant Award Summary Clemson University received a $250,120 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded August 15, 2025, with completion targeted for July 31, 2028. The primary deliverable is the development of specialized microfluidic devices designed to investigate the effects of cellular deformation on cell proliferation and motility....
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a Project Grant of $179,471 to Trustees of Tufts College on November 15, 2025, under the Engineering program (CFDA 47.041) for a CAREER award titled "Unveiling the Stability, Rheology, and Topology of Active Fluids." This award supports fundamental research into active fluids—suspensions of self-propelled particles that convert locally...
- Federal Grant Award Summary Princeton University received a $600,000 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective June 1, 2026 through May 31, 2031. The project will develop three-dimensional biomechanical sensing technologies to map mechanical properties in living tissues during vertebrate development. Key deliverables...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $574,808 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective May 1, 2025 through April 30, 2030. This CAREER award supports fundamental research to understand and control cellular heterogeneity in chimeric antigen receptor (CAR) T-cell populations through advanced...
- Federal Grant Award Summary Emory University received a $500,001 CAREER (Faculty Early Career Development) Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (Engineering program, CFDA 47.041) effective June 1, 2026, through May 31, 2031. This award supports the development of high-precision phototoxic subtractive tissue engineering technology that uses spatially patterned light to selectively induce apoptosis in...
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- Federal Project Grant Award Summary Tulane University received a $270,855 Project Grant award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041, Engineering program) effective April 1, 2026, through March 31, 2029. This collaborative research project will develop advanced catalyst designs to improve the selective conversion of lignin—a major biomass component—into fuels and valuable chemicals through...
- Federal Grant Award Summary The University of New Mexico's Office of Sponsored Projects received a $517,390 Faculty Early Career Development (CAREER) award from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective October 1, 2025 through July 31, 2027. This project grant supports fundamental research to develop mechanistic understanding of how multiscale biophysical cues—including stiffness,...
Tulane University received a $814,266 CAREER award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective July 1, 2026 through June 30, 2031. The award supports research utilizing microphysiological systems (MPS)—bioengineered microtissues that replicate complex tissue environments—to investigate the molecular mechanisms of pathological angiogenesis, specifically how blood vessel growth becomes abnormal in diseases such as cancer. The research employs vessel-on-a-chip and tumor-on-a-chip MPS models to study endothelial-to-mesenchymal transition (pEndoMT) and its regulation by growth factors and fluid flow dynamics, with the objective of generating ordinary differential equation (ODE) models and identifying unique biomarkers relevant to disease processes. In parallel with its research activities, the project delivers comprehensive educational programming and workforce development initiatives designed to increase public awareness of MPS technology, promote adoption of MPS methodologies in basic research, and enhance STEM (Science, Technology, Engineering, and Mathematics) education pipeline retention among students. Through these integrated research and educational components, the award advances biomanufacturing and biomaterials capabilities while preparing the scientific workforce for future integration of MPS technology into translational research and basic biological principle applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $814.3k | 5/26/26 |