Project Grant 2542804
- This $210,720 federal project grant was awarded by the National Science Foundation (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences federal grant program (CFDA 47.049). The project aims to define modular structures in biological systems in a mathematically rigorous way, and determine how modularity can be advantageous to organisms and advance the understanding of molecular systems. The research will study the modularity of gene regulatory networks underlying...
- Federal Grant Award Summary Northeastern University received a $498,240 Project Grant from the National Science Foundation's Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2028. The award supports the development of advanced cyberinfrastructure to enable Findable, Accessible, Interoperable, and Reusable (FAIR) use of single-cell proteomics (SCP) data. Key deliverables include the formalization of open...
- Federal Project Grant Award Summary Northeastern University received a $300,000 Project Grant from the National Science Foundation's Division of Mathematical Sciences (CFDA 47.049) awarded July 1, 2026, with completion scheduled for June 30, 2029. This collaborative research initiative will develop novel machine learning methodologies operating on stratified matrix manifolds under group actions, integrating topology, geometry, and machine learning to advance data-enabled discovery. The project...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $422,500 to the Mount Desert Island Biological Laboratory under the Biomedical Research and Research Training program (CFDA 93.859) beginning April 1, 2026, with completion targeted for January 31, 2031. This Project Grant supports fundamental research investigating the molecular mechanisms underlying limb and tail regeneration in axolotls, with the objective of identifying biological pathways that...
- This federal Project Grant award of $116,354, provided by the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049), supports collaborative research to develop a mathematical theory for the biological concept of modularity. The research aims to define modular structures in biological systems, such as gene regulatory networks underlying salamander limb regeneration and hormone regulation in plants, in a...
- Federal Project Grant Award Summary Northeastern University received a $509,000 Project Grant from the National Science Foundation's Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, through August 31, 2028. This collaborative research initiative investigates mechanoadaptation in skeletal structure across the genus Peromyscus (deer mice) by examining how bone morphology responds to behavioral and environmental factors...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Biological Infrastructure awarded a $464,952 Research Experiences for Undergraduates (REU) Site grant to the Mount Desert Island Biological Laboratory in Bar Harbor, Maine (CFDA 47.074, Biological Sciences) effective April 15, 2026, through March 31, 2029. This REU Site provides comprehensive undergraduate research training and mentorship across three summer sessions (2026–2028), supporting ten students annually in...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Mathematical Sciences awarded The Johns Hopkins University a Project Grant of $209,998 on August 15, 2025, under the Mathematical and Physical Sciences program (CFDA 47.049). This project, scheduled for completion by July 31, 2028, develops mathematical and computational tools to learn the dynamics of complex high-dimensional systems from ensemble data—observational snapshots rather than complete trajectories. The...
- Federal Project Grant Award Summary The Johns Hopkins University received a $900,000 Project Grant from the National Science Foundation's Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2028. This award supports research examining the mechanistic roles of hyper-divergent genomic regions in gene-by-environment interactions using nematode species as model organisms. The research employs advanced genomics...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $440,000 to the University of Massachusetts Boston under the Biological Sciences program (CFDA 47.074) on July 1, 2026, for a three-year collaborative research project examining the evolution of neurons through messenger ribonucleic acid (mRNA) regulation. This project will deliver fundamental research outputs investigating whether regulatory mechanisms controlling...
The National Science Foundation Division of Mathematical Sciences awarded Northeastern University a $674,161 Project Grant (CFDA 47.049, Mathematical and Physical Sciences program) effective August 1, 2026, through July 31, 2031, to develop a multiscale computational framework for understanding tissue regeneration in model organisms such as axolotls. The project delivers an integrated suite of open-source computational tools and mathematical models that connect individual cell-level dynamics to large-scale tissue morphogenesis by combining continuum mechanics, stochastic agent-based modeling, neural network operator learning, and data-driven parameter inference. The research focuses on identifying the cellular and mechanical processes governing blastema formation during limb regrowth, with potential applications in biotechnology, regenerative medicine, wound healing, and engineered tissue development. In addition to core research deliverables, the grant supports educational and community engagement products, including undergraduate research opportunities, quantitative learning modules designed for life science students, and hands-on outreach activities introducing computational thinking and biological pattern formation to K-12 students in the Boston, Massachusetts area. These integrated products advance both regenerative biology research capabilities and broader access to computational approaches within the life sciences discipline.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $674.2k | 7/1/26 |