Project Grant 2529743
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program provides $116,000.00 in funding to Brown University to investigate how the shape of limb bones in deer mice is influenced by both genetic inheritance and physical activity during an animal's lifetime. The key products and services to be delivered under this award include: Studying two closely related species of deer mice, one that burrows underground and one that does not, to...
- This three-year Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $198,298 to Bucknell University to research the effects of miniaturization on the vertebral bone structure of small mammals. The university will utilize 3D imaging, computer modeling, and physical testing to examine how size impacts the backbone structure and function of shrews, moles, hedgehogs, and solenodons. Researchers aim to determine if smaller bones are stronger or...
- This $484,370 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research into the challenges of living small for diminutive mammals. The Field Museum of Natural History will leverage the taxonomic diversity of shrews, moles, hedgehogs, and solenodons to quantify selective pressures on vertebral bone strength and stiffness at small sizes. Researchers will use 3D imaging, computer modeling, and physical testing to assess how lumbar spines have...
- The National Science Foundation, under its Biological Sciences program (CFDA 47.074), awarded Carroll College a $179,949 Project Grant to study the multilevel effects of urbanization on the health of the western deer mouse. This 3-year research project aims to identify the key factors that impact wildlife health in urban areas, as the deer mouse inhabits both urban and rural environments. Researchers will collect data on habitat characteristics and mouse health metrics, such as immune function...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $280,000 over 3 years to Auburn University to investigate the roles of mitochondrial behavior and morphology in animal performance. The key objectives are to test the hypotheses that: 1) changes in mitochondrial shape and movement increase ATP production, and 2) mitochondrial characteristics play critical roles in how animals respond to factors like food availability,...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $670,175 to the University of Washington to investigate the ecomorphology and evolution of sexual dimorphism in mammalian skulls. The key research activities include: Measuring traits such as size, shape, biting ability, bone structure, and bone strength of carnivoran mammal skulls using 3D scanning and computer modeling techniques. Analyzing differences in skull form and...
- This Project Grant awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) supports research to understand how human bone tissue dynamically adapts at the nanoscale level under various loading conditions. The $719,538 award to the Trustees of the University of Pennsylvania, made on May 1, 2024, will investigate the real-time rearrangement and deformation of the nanoscale components of healthy and osteoporotic bone tissue when subjected to cyclic loading....
- This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports a postdoctoral research fellowship to investigate the genomic basis of rapid urban adaptation in house mice. The $240,000 award, effective December 1, 2024 through November 30, 2027, will enable the fellow to: 1) characterize temporal shifts in urban mouse population structure and genetic diversity, and 2) identify genomic signatures of rapid adaptation to urban...
- This Project Grant from the National Science Foundation, under the Biological Sciences program (CFDA 47.074), provides $656,957 to the Regents of the University of California, Berkeley for the period of September 15, 2021 through August 31, 2024. The grant supports research entitled "INTBIO: Disentangling the Genetic, Biomechanical, and Deep-Time Factors Underlying Mammalian Skeletal Diversity." The University will conduct research into the genetic and evolutionary factors that have...
- This three-year $295,671 Project Grant from the National Science Foundation's Social, Behavioral, and Economic Sciences program will support research and training activities at the University of Missouri aimed at validating patterns of bone functional adaptation in living humans. The principal investigator will analyze computed tomography scan data from living individuals to investigate relationships between muscle size, bone strength in different body regions, and self-reported activity...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $509,000.00 to Northeastern University to conduct research on how bone structure is shaped by genetic inheritance versus physical activity in deer mice. The 3-year project investigates the mechanisms of "mechanoadaptation" - how bones change shape in response to different behaviors and environments - using deer mice as a model organism. By raising mice in digging versus non-digging environments and using advanced X-ray imaging, the researchers will discover how specific behaviors reshape bone structure. The findings have implications for understanding bone diseases, aging, and the role of exercise in maintaining skeletal health. The project will also advance scientific infrastructure by pioneering new imaging technology, train students, and create educational materials on evolution, physiology, and engineering principles. This work addresses a fundamental question in biology about how form follows function in living organisms.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $509.0k | 7/23/25 |