Project Grant 2542013
- Federal Grant Award Summary The University of Michigan received a $219,999 Faculty Early Career Development (CAREER) Project Grant award dated December 15, 2025, from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041). The project, which extends through December 31, 2027, delivers research and development products focused on engineering instructive microenvironments to guide single stem cell...
- Federal Project Grant Award Summary The University of Michigan received a five-year CAREER Project Grant totaling $599,998 from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041 - Engineering program), effective July 1, 2025 through June 30, 2030. The grant supports fundamental research investigating how surface topographies and physical properties of biomaterials influence immune cell behavior and host-pathogen...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $549,998 to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) through a Faculty Early Career Development (CAREER) grant, effective February 15, 2026 through January 31, 2031. This project grant develops ultrasensitive single-molecule protein detection technologies and platforms designed to simultaneously measure...
- Federal Grant Award Summary The University of Michigan received a $400,000 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective September 1, 2025 through August 31, 2028. This collaborative research project delivers fundamental scientific knowledge and experimental/theoretical models investigating the mechanics of tissue boundary formation during embryonic development. The primary...
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $199,991 to the University of Michigan-Dearborn under the Engineering program (CFDA 47.041) on May 15, 2026, through an Engineering Research Initiation (ERI) grant. This two-year project, with completion scheduled for April 30, 2028, will deliver a novel microphysiological system that simulates the brain's cerebrospinal fluid (CSF) environment and...
- Federal Project Grant Award Summary The University of Michigan received a $329,020 CAREER award from the National Science Foundation (NSF), Division of Information and Intelligent Systems, under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), effective June 15, 2025, through May 31, 2030. This project grant funds the development of novel analytical methodologies and computational tools designed to enable causal inference and robust statistical modeling on...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $574,808 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective May 1, 2025 through April 30, 2030. This CAREER award supports fundamental research to understand and control cellular heterogeneity in chimeric antigen receptor (CAR) T-cell populations through advanced...
- Federal Grant Award Summary The National Science Foundation's Division of Electrical, Communications and Cyber Systems awarded $550,000 to the University of Michigan under the Engineering program (CFDA 47.041) to develop an injectable transponder system for precise radiotherapy tumor targeting and dosimetry. This five-year Faculty Early Career Development (CAREER) award, effective April 1, 2026 through March 31, 2031, funds research to create a minimally invasive, implantable medical device that...
- Federal Grant Award Summary Michigan State University received a $550,000 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective September 1, 2025 through August 31, 2030. The project develops advanced electrode interfaces and synthetic nicotinamide adenine dinucleotide (NADH) mimics to enable selective and rapid electrochemical...
- Federal Project Grant Award Summary Michigan State University received a $437,093 Faculty Early Career Development (CAREER) Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded November 15, 2025, with completion targeted for October 31, 2029. The primary deliverable is the development of photoacoustic-Brillouin microscopy (PABM), an innovative non-contact,...
The University of Michigan received a $605,420 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective May 1, 2026 through April 30, 2031. This project grant funds fundamental research to decipher T cell reprogramming mechanisms toward biomanufacturing of regulatory T cells (Tregs). The primary deliverable is advanced scientific knowledge regarding how conventional T cells are naturally reprogrammed into Tregs through cell-cell communication, utilizing an engineered three-dimensional culture system that replicates natural cellular microenvironments. This research addresses a critical gap in understanding Treg generation, which currently limits the therapeutic potential of induced Tregs produced in vitro for treating inflammatory diseases including diabetes, Alzheimer's, asthma, and heart disease. In addition to research outputs, the award requires development and delivery of an integrated education and outreach program emphasizing scientific communication skills. The project will generate novel methodologies and mechanistic insights into T cell reprogramming that could enable improved biomanufacturing of therapeutic Tregs for clinical applications requiring restoration of immune system balance between inflammation and self-tolerance. The five-year funding period supports both technical innovation and workforce development, consistent with NSF Engineering program emphasis on advancing excellence in engineering research while fostering a skilled workforce.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $605.4k | 4/8/26 |