Project Grant 2533047
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $629,896 Project Grant to the University of Wisconsin-Madison on February 15, 2021 with a completion date of January 31, 2026. The grant supports research under the Biological Sciences program (CFDA 47.074) to advance understanding of heterogeneous decision-making in individual microbes and populations through synthetic approaches. As the official program description indicates, the Biological Sciences...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $1,000,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Madison. The 3-year grant, effective September 1, 2023, supports a collaborative research project between the University of Wisconsin-Madison and members of the Department of Energy's Agile Biofoundry to investigate bacterial transporters and engineer them for superior properties in...
- This federal Project Grant award, valued at $596,920 and provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041), aims to develop a mechanism-informed AI platform to optimize biomanufacturing processes for life-saving biopharmaceuticals. Led by Northeastern University, the project will leverage emerging sensing technologies to efficiently decode the fundamental mechanisms underlying complex biomanufacturing systems. The goal is to create a flexible and robust AI-based...
- This $525,899 National Science Foundation project grant supports the development of Ecology-Knowledge Guided Machine Learning (Eco-KGML) models to advance understanding of lake water quality dynamics across spatial and temporal scales in the United States. Funded under the Biological Sciences program (CFDA 47.074), the University of Wisconsin-Madison will utilize hybrid process-based and machine learning techniques to predict and analyze metrics such as water clarity, phytoplankton biomass,...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $500,000 Project Grant under the Biological Sciences (CFDA 47.074) program to The Ohio State University. The 2-year award, effective October 1, 2023, supports research to understand and mitigate factors limiting continuous production in industrial fermentation processes. The project will focus on developing novel synthetic biology tools and advanced bioprocesses to convert abundant biomass and waste...
- The National Science Foundation (NSF), under its Biological Sciences program (CFDA 47.074), awarded the University of Wisconsin System $621,502 on August 15, 2023 for a project titled "COLLABORATIVE RESEARCH: EDGE FGT: DEVELOPMENT OF A COMPREHENSIVE SELECTION LIBRARY TO RECONCILE CORE METABOLIC KNOWLEDGE GAPS". The project aims to develop tools and resources (algorithms, strains, and plasmids) to rapidly identify the functions of genes in non-model organisms, in order to better...
- The National Science Foundation awarded a $325,309 Project Grant to the University of Massachusetts Lowell's Office of Research Administration to support collaborative research titled "CONTINUOUS BIOMANUFACTURING USING DECOUPLED GROWTH AND PRODUCTION STAGES FOR EFFICIENT PRODUCTION AND RECOVERY." The research is funded under the NSF Directorate for Engineering's CFDA #47.041 Engineering program and aims to improve biomanufacturing processes through continuous and decoupled growth and...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $100,000 Project Grant to the Georgia Tech Research Corporation on July 1, 2025. The grant supports a collaborative research project titled "ACED: Accelerating Protein Engineering with Evolution-Guided Generative AI and a Self-Driving Biofoundry." The project aims to advance protein engineering by combining cutting-edge artificial intelligence (AI) methods with automated laboratory...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences and the Division of Chemical, Bioengineering, Environmental and Transport Systems awarded a $240,000 Project Grant to the University of California Irvine (UC Irvine) under the NSF Biological Sciences program (CFDA 47.074). The grant supports collaborative research to develop unnatural cofactors that can be deployed as stronger-than-nature thermodynamic driving forces in biomanufacturing processes. This is...
- This federal Project Grant award of $450,000.00 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports the development of an "In Vitro Biomanufacturing on a Chip (IBOC)" system. The IBOC technology aims to enhance in vitro prototyping of bioproduction pathways by providing rapid sensing feedback to optimize enzyme combinations and metabolic flux. This approach is expected to accelerate strain development timelines, reduce reliance on empirical...
The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $500,000 Project Grant to the University of Wisconsin-Madison to develop a machine learning model for rapid assessment of technical and economic impacts of process perturbations in biomanufacturing. This 2-year project (8/1/2025 - 7/31/2027) aims to deliver a decision-making tool to enable predictable scale-up and consistently near-optimal performance for new fermentation processes, which is critical for building financially viable biomanufacturing facilities. The project leverages recent advances in machine learning, insights from an industry partner, and data collected across scales from benchtop to commercial processes. It also provides research experiences for undergraduate students and supports outreach science activities to K-12 students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $500.0k | 7/22/25 |