This $500,000 Project Grant from the National Science Foundation Division of Materials Research supports the development of antibody-mimicking polymeric nanoparticles for site-specific protein labeling and protein-binding applications. Funded under the Mathematical and Physical Sciences program (CFDA 47.049), Professor Yan Zhao at Iowa State University will pursue two aims - site-specific labeling of proteins with single or multiple tags using the nanoparticles, and developing nanoparticle receptors to bind protein surface groups. The nanoparticles are prepared through molecular imprinting within cross-linked surfactant micelles and are expected to impact multiple research fields including biochemistry, cell biology, biotechnology, and protein therapeutics. Iowa State University serves as the sub-awardee, performing the technical work outlined in the grant with an award period from April 15, 2023 through March 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $500.0k | 4/10/23 |