Project Grant 2531822
- This federal Project Grant award for $350,993 was provided by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program to Lincoln University, a historically Black college and university (HBCU) in Pennsylvania. The project, titled "COLLABORATIVE RESEARCH: OUT OF ONE, MANY: PARALOG-SPECIFIC REGULONS FROM A SINGLE NETWORK ARCHITECTURE", aims to map the underlying regulatory properties of transcription factor functional divergence - a key driver of cellular and...
- This $406,250 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports two primary research directions at the University of Pennsylvania. The first research direction focuses on understanding how transcription factor families coordinate complex developmental pathways to generate diverse cellular morphologies and cell types, with a focus on identifying new mechanisms of transcription...
- The Pennsylvania State University (Penn State) received a $608,569 Project Grant award from the National Science Foundation (NSF) on September 1, 2021 to develop a predictive biophysical model of transcription rate across cellular conditions. The award is part of the NSF's Biological Sciences program (CFDA 47.074) and will support research through August 31, 2024 to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increased knowledge and...
- This federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $776,309 to The Pennsylvania State University to conduct research on the structural responses of intrinsically disordered proteins to chemical modifications that regulate gene expression. The project aims to develop new experimental methodology for nuclear magnetic resonance (NMR) spectroscopy to gain quantitative insights into these regulatory mechanisms. The research...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $200,000 in funding to The Trustees of the University of Pennsylvania to conduct collaborative research that aims to understand genomic organization in the cell nucleus. The research team will employ an integrated approach leveraging biophysical modeling, super-resolution imaging, and machine learning to develop predictive models of how chromatin structure and...
- The Trustees Of The University Of Pennsylvania received a $875,000 Project Grant award from the National Science Foundation Division of Environmental Biology. The grant funds research on "The Evolutionary Significance of Genetic Pleiotropy in Species Interactions" from September 1, 2021 through August 31, 2024. The research aims to advance understanding of major problems in biological sciences, as outlined in the Biological Sciences program (CFDA 47.074) of the National Science...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $300,000 in funding to Western University of Health Sciences to conduct collaborative research on the variability and regulation of the plant polyadenylation complex. The research aims to better understand how this complex mediates gene expression and plant responses to environmental and developmental cues, with the goal of improving our knowledge of crop plant growth,...
- The University of Delaware was awarded a $950,000 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences. The grant is part of the NSF's Biological Sciences program (CFDA 47.074) and will fund research into post-transcriptional regulation during mitosis from July 2021 through June 2025. As part of the Biological Sciences program's goal of strengthening the nation's biological research enterprise, this project aims to increase scientific understanding of...
- This Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) provides $179,978.00 to South Dakota State University to conduct research on the mechanistic regulation of dynamic gene expression patterns by temporal JNK activation. The project aims to expand understanding of how cells process information and respond to stress, with a focus on two key mechanisms: post-transcriptional regulation of genes through mRNA stability and combinatorial...
- The National Science Foundation awarded a $138,000 Project Grant to support research activities from November 1, 2021 to October 31, 2023 under the Biological Sciences program (CFDA 47.074). The grant funding will enable the grantee to conduct research at the University of Pittsburgh aimed at furthering understanding of the evolution of gene regulatory networks through empirical and theoretical approaches. The Biological Sciences program seeks to advance the field and strengthen the national...
This $900,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program will support collaborative research at the University of Pennsylvania and Lincoln University to investigate the mechanisms of transcription factor functional divergence. The research aims to map the regulatory properties of a process known as "differential usage of shared binding sites", which drives cellular and organismal complexity through the evolution of transcription factor families. Key goals include building research capacity at the undergraduate institution, Lincoln University, and providing a paired summer research experience for students at the University of Pennsylvania. The award duration is from September 15, 2025 through August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $900.0k | 8/5/25 |