Project Grant 2531367
- This $300,000 project grant, awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), is focused on collaborative research to deepen the understanding of biofilm development and growth in constrained environments. The project aims to leverage highly tunable bacterial biofilm systems as a model to study the mechanics and morphogenesis of biological growth processes. Through a combination of confocal imaging, data analysis, and theoretical modeling, the...
- This $265,007 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support collaborative research to advance the understanding of bacterial swimming motion. The research aims to leverage robophysical modeling techniques from robotics to realistically emulate and study the complex interplay of physical and biological factors governing bacterial motility behaviors. Key objectives include elucidating how fluid mechanical forces shape the ways...
- The National Science Foundation awarded a $934,613 project grant to Princeton University on July 1, 2021, with a completion date of June 30, 2024. The grant supports research under the Biological Sciences program (CFDA 47.074) to study quorum sensing control of bacterial biofilm formation and dispersal. The funding will allow Princeton University researchers to advance scientific understanding of how bacteria communicate to form biofilms and disperse, with the goal of gaining fundamental...
- This $1,230,301 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports a multidisciplinary collaboration to explore the mechanical properties and genetic/biochemical basis of a potent adhesive biopolymer produced by bacteria. The research aims to provide a detailed mechanistic understanding of how these types of materials impart strong adhesion, with applications in developing biocompatible and water-tolerant adhesives. The award,...
- This National Science Foundation (NSF) Project Grant award under CFDA Program 47.041 - Engineering, in the amount of $232,786, will support collaborative research on robophysical modeling of bacterial swimming motion. The project aims to advance the understanding of how fluid mechanical forces shape the ways bacteria navigate their complex environments and interact with each other. By adopting techniques of robophysical modeling, the researchers will isolate physical effects governing...
- This federal Project Grant award of $120,000 from the U.S. Department of Defense's Basic Scientific Research Program (CFDA 12.431) was granted to Yale University on February 15, 2025, with a performance period ending on February 14, 2028. The objective of this research project is to uncover the self-organizing principles that dictate the molecular architecture of bacterial biofilm extracellular polymeric matrices and how those design principles contribute to the function of this matrix....
- This federal Project Grant award titled "CAREER: DEFINING BACTERIAL EXTRACELLULAR VESICLE BIOGENESIS AND INTERACTIONS WITHIN THE HOST ENVIRONMENT" was provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041) in the amount of $671,681 with a period of performance from July 1, 2025 to June 30, 2030. The grant is intended to advance fundamental understanding of bacterial extracellular vesicle (BEV) biology and signaling within the vaginal microbiome. The key...
- The National Science Foundation awarded a $548,102 project grant under the Engineering (47.041) program to the University of Texas at Austin to develop a predictive framework for understanding how bacteria sense and respond to surface mechanics upon attachment. The three-year award beginning April 1, 2022 will support research using atomic force microscopy, high-throughput culturing, finite element modeling, quantitative confocal microscopy, and genetic manipulation to characterize the stresses,...
- This $160,000 federal Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research on the spatiotemporal dynamics of intercellular signaling in growing bacterial populations. The research aims to develop mathematical modeling techniques to better understand and predict the behavior of engineered multicellular bacterial systems, which have potential applications in areas like gut microbiome...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) award of $1,000,000 to the Regents of the University of Minnesota aims to design and control the formation of a robust artificial biofilm consortium composed of two bacterial species for the efficient biodegradation of polyfluorinated compounds (PFAS) known to accumulate in the environment. The project will establish the knowledge base and design principles as a framework for developing and manufacturing...
This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports a collaborative research project focused on understanding the mechanics and morphogenesis of bacterial biofilms. The award, with an effective date of December 1, 2025 and a completion date of November 30, 2028, will enable researchers at Yale University to conduct detailed observations and theoretical modeling of biofilm growth under varying environmental conditions, such as geometrical constraints and nutrient availability. The overarching goals are to deepen the understanding of biofilm development in constrained environments and leverage the growth of highly tunable biofilm systems as a generic model for biological growth. The project aims to derive theoretical models that integrate the essential mechanisms driving biofilm morphogenesis, with the ultimate goal of exposing new rules and unexpected phenomena in this area of research, which has direct implications for our understanding of bacterial biofilm resilience.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.0k | 8/20/25 |