The National Science Foundation awarded the University of Virginia a $133,333 project grant under the Engineering federal grant program (CFDA 47.041). The grant will fund a collaborative research project investigating the role of microenvironments, manufacturing processes, and metabolism on mesenchymal stromal cell production of extracellular vesicles. Specifically, the University will examine the effects of three-dimensional hydrogel microenvironments and manufacturing strategies on...
This $265,007 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support collaborative research to advance the understanding of bacterial swimming motion. The research aims to leverage robophysical modeling techniques from robotics to realistically emulate and study the complex interplay of physical and biological factors governing bacterial motility behaviors. Key objectives include elucidating how fluid mechanical forces shape the ways...
This National Science Foundation (NSF) Engineering program grant award, titled "CAREER: BACTERIAL EXTRACELLULAR VESICLES IN WASTEWATER SYSTEMS: PERSISTENCE AND PRODUCTION TO DISSEMINATE VIRULENCE PROTEINS", was provided to the Research Foundation for the State University of New York (RF SUNY), a non-profit organization, to conduct research on bacterial extracellular vesicles in wastewater systems. The $467,262 award, which began on May 1, 2024 and runs through April 30, 2029, aims to...
The National Science Foundation (NSF) has awarded a $549,999 Project Grant under its Engineering program (CFDA 47.041) to George Washington University. This 5-year award, effective August 1, 2025, aims to elucidate the impact of bacterial association on the infectivity, environmental persistence, and disinfection resistance of enteric viruses. The research will investigate the occurrence, abundance, and removal of emerging bacteria-associated viruses in wastewater treatment and natural...
The National Science Foundation (NSF) awarded a $563,387 Project Grant under the Biological Sciences program (CFDA 47.074) to The University of Mississippi to investigate the function of an unknown bacterial protein and its role in pilus biogenesis. The project will characterize how this conserved protein, called BRESU_2828, influences the synthesis of bacterial pili, which are surface structures used for attachment and biofilm formation. The research aims to provide insights into the mechanisms...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $441,868 Project Grant to the University of Houston System (UH) to investigate bacterial persistence and antibiotic tolerance, a critical global public health challenge. The primary research objectives are to: (1) utilize high-throughput screening and genomic sequencing to identify genes important for bacterial persistence, (2) validate potential persistence-mediating mechanisms, and (3) conduct genetic studies...
This National Science Foundation (NSF) Project Grant award under CFDA Program 47.041 - Engineering, in the amount of $232,786, will support collaborative research on robophysical modeling of bacterial swimming motion. The project aims to advance the understanding of how fluid mechanical forces shape the ways bacteria navigate their complex environments and interact with each other. By adopting techniques of robophysical modeling, the researchers will isolate physical effects governing...
The National Science Foundation (NSF) awarded a $195,656 Project Grant under its Engineering program (CFDA 47.041) to the University of Cincinnati for a collaborative research study on the collective dynamics of multiple bacterial flagella. This 3-year project, starting on July 1, 2024, aims to understand how the flagellar filaments of peritrichous bacteria, such as E. coli, synchronize and rotate collectively to enable swimming in fluid media. The research will integrate macroscopic model...
The University of Maryland, College Park will receive $536,244 from the National Science Foundation under the Engineering federal grant program (CFDA 47.041) for a project grant titled "Engineering Host-Pathogen Interactions to Understand Influenza A Infection." The funding, awarded on October 1, 2022 and set to be completed by September 30, 2025, will support research examining the physical and biochemical factors that influence how influenza A virus penetrates and overcomes the...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $719,638 to Cornell University to conduct fundamental research on the nanomechanics of bacterial adhesion and growth on healthy and diseased human gut mucus. The research aims to determine how differences in the molecular structures of healthy and diseased gut mucus impact bacterial adhesion and biofilm formation. The project will use computational modeling and simulations to obtain...