Project Grant 2530428
- This $3 million National Science Foundation project grant supports research at the University of Texas at Austin to develop synthetic adhesive cells for controlled intracellular delivery. Funded under the Biological Sciences program (CFDA 47.074), the three-year award will engineer synthetic cells with user-defined control over molecular transfer between synthetic and live cells. Researchers will build on prior work developing synthetic cells that form adhesive junctions and transfer cargo...
- This federal Project Grant, awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $621,980.00 to the University of Texas at Dallas to develop "sliding hydrogel-based microparticles as synthetic platelets" for managing traumatic bleeding. The project aims to create a novel hemostatic agent that can be administered intravenously to...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $1,028,700 to the University of Texas at Austin to investigate a previously unknown mechanism by which proteins on cell surfaces transmit information across membrane boundaries. The project aims to elucidate the fundamental biophysical mechanisms behind this "transbilayer coupling" of protein condensates, which could lead to new ways of controlling cellular behavior for...
- The National Science Foundation (NSF) awarded a $300,000 Project Grant to the University of Chicago for the "BRING-SYNBIO: DYNAMIC COOPERATIVE BINDERS FOR ENDOGENOUSLY GATED CELLULAR CONTROL" project under the NSF Engineering program (CFDA 47.041). This project aims to develop a new class of intrinsically disordered proteins that can directly sense environmental cues and trigger rapid, targeted changes in cellular responses, such as directing tumor cells to break apart and die. The...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,299,732 to the University of Texas at Austin under a Project Grant to support research titled "COLLABORATIVE RESEARCH: SYNTHETIC AND SYSTEMS BIOLOGY APPROACHES TO SEMI-SYNTHETIC CELLS WITH EXPANDED DNA ALPHABETS." The three-year award beginning August 15, 2021 falls under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and strengthen the Nation's...
- This National Science Foundation (NSF) federal Project Grant award under the Biological Sciences program (CFDA 47.074) is funding the University of Illinois to construct a new type of self-replicating synthetic cell system. The $448,355 award from June 1, 2024 to May 31, 2027 supports the development of engineered synthetic cells that can grow, divide, and replicate their genetic information using nucleic acids as both structural and genetic components. The project aims to investigate the...
- This $305,394 CAREER award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports fundamental research and education activities in capillary-incorporated bioprinting of biomimetic soft tissue constructs at the University of Houston System. The project investigates a hybrid bioprinting technology that combines electrospinning of porous microtubes and hydrogel layers to create scaffolds with life-sustaining capillaries, aiming to advance regenerative medicine...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Rice University a $373,174 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to advance biological knowledge and understanding of major problems to strengthen the nation's scientific enterprise....
- This National Science Foundation Project Grant award of $937,018 provides funding for collaborative nanoscience research between the University of Texas at El Paso and Baylor College of Medicine. The award is made under the NSF Engineering Directorate's 47.041 CFDA program to support innovation and excellence in engineering research. Specifically, the researchers will investigate the influence of physical and chemical factors of nanomaterials on cell adhesion, protein synthesis, and cellular...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) is supporting a collaborative research effort focused on developing an intelligent lab-on-chip device to monitor and promote the maturation of stem cell-derived cardiomyocytes. The $192,150 award to the New York Institute of Technology (NYIT) aims to create an integrated system that can non-invasively evaluate cardiomyocyte maturity in real-time and adaptively apply electrical and mechanical...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $1,332,516.00 to the University of Texas at Austin to develop synthetic cells that mimic the essential functions of biological platelets. The project aims to create light-activated, programmable synthetic cells that can undergo shape transformation, release biochemicals, and adhere to surfaces in a coordinated manner to promote blood clotting. This work addresses the critical need for a solution to the shortage of donor platelets used in trauma care, surgery, and cancer treatment. The project also integrates cutting-edge research with multi-level educational outreach to train the next generation of scientists and engineers. The award has an effective date of August 15, 2025 and an ultimate completion date of July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 7/22/25 |