Project Grant 2527934

Award Date 7/15/25
Completion Date 6/30/26
Dollars Obligated $305K
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Benicia, CA 94510, USA
Similar Awards
This Project Grant award of $305,000 from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program will support the development of a novel mammalian cell-based nano-biological coating for implantable medical devices at Novaurum Biosciences Incorporated in Somerville, MA. The project aims to address the critical issue of implant-related infections, which cost the U.S. healthcare system over $8.6 billion annually, by creating a biocompatible and...
This $515,926 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) will fund research to develop an in vitro gingival (gum) tissue system to study the role of microbial communities on oral health and disease. The 5-year project, beginning June 1, 2024, will be conducted by the University of Massachusetts Lowell's Office of Research Administration-Lowell. The key objectives are: (1) developing and validating a microphysiological system to study oral...
The National Science Foundation (NSF) awarded a $271,443 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to Mammae Biosciences, Inc., a minority-owned, for-profit, woman-owned business and manufacturer, to develop an enzymatic method to produce compounds found in human milk at commercial scale. The goal is to assess an affordable enzymatic process for generating marketable natural compounds usually found in human milk, such as N-acetylglucosamine...
This Project Grant award of $275,000, funded by the National Science Foundation (NSF) under the CFDA program 47.084 "NSF Technology, Innovation, and Partnerships", aims to develop improved bacterial strains for more cost-effective production of proteins used in detergents, personal care products, and dairy. The project seeks to identify superior bacterial hosts and develop advanced genetic engineering tools to convert these bacteria into efficient protein factories. The goal is to...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $719,638 to Cornell University to conduct fundamental research on the nanomechanics of bacterial adhesion and growth on healthy and diseased human gut mucus. The research aims to determine how differences in the molecular structures of healthy and diseased gut mucus impact bacterial adhesion and biofilm formation. The project will use computational modeling and simulations to obtain...
This Project Grant award of $305,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of an advanced wound care product for treating diabetic foot ulcers. The product is a microneedle bandage that delivers three therapeutic agents to disinfect the wound, prevent bacterial biofilm re-formation, and activate the immune system to facilitate healing. Initial work will be conducted using skin tissue cultures and testing...
The Massachusetts Institute of Technology (MIT) was awarded a $800,000 Project Grant from the National Science Foundation (NSF) to conduct collaborative research titled "Learning How Mucus Shapes and Maintains Microbiomes" from September 1, 2021 through August 31, 2026. Under the award, MIT researchers will work to advance understanding of the role that mucus plays in shaping and maintaining microbiomes. The research is funded through the NSF's Biological Sciences program (CFDA...
This three-year, $374,681 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports the development of new biomimetic polymers that emulate natural mucins. The awardee, The Trustees of the University of Pennsylvania, and its sub-awardee, the City University of New York, will synthesize homopolymer, copolymer, and triblock copolymer mucin analogs. Researchers will systematically study how synthetic mucin structure impacts rheological,...
The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
This Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) provides $104,236.00 to support a team of undergraduate students from the University of Virginia in developing a low-cost, non-invasive, effective topical treatment for Staphylococcus-based cellulitis. The project aims to produce skin-penetrating antimicrobial peptides specific to Staphylococcus with the potential for scalable production. Through this effort, the students will receive hands-on...

This Project Grant award of $305,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a platform of biomimetic mucins to address recurrent bacterial infections. The awardee, Kapha Bio, Inc., aims to create a library of biomimetic mucins that can be incorporated into personal care and dietary supplements to restore mucosal tissue homeostasis and reduce infection and recurrence rates for conditions like gum disease, irritable bowel syndrome, and bacterial vaginosis. The key products to be delivered include: (1) a library of biomimetic mucins screened for antimicrobial and anti-biofilm activities against pathogenic bacteria, (2) confirmation of the cytocompatibility of the biomimetic mucins with human epithelial cells, and (3) identification of top-performing biomimetic mucin variants for scaled-up manufacturing and commercialization. This award reflects NSF's mission to advance scientific research and innovation to address national and societal challenges.

Generated 8/5/25, 5:25 AM