Project Grant 2338518
- The National Science Foundation awarded Cornell University a $459,414 Project Grant under the Engineering federal grant program (CFDA 47.041) to support research titled "The Fluid Mechanics of Bacterial Swimming in Yield Stress Fluids" from December 1, 2021 through November 30, 2024. The grant funding will enable Cornell researchers to study the swimming behavior of bacteria in non-Newtonian fluids that exhibit a yield stress, providing insight into bacterial locomotion in environments...
- The National Science Foundation awarded Cornell University a three-year Project Grant totaling $430,000 under the Engineering program (CFDA 47.041) to support research titled "Mechanoregulation in the Maintenance of the Bacterial Cell Wall." From May 2021 through April 2024, Cornell researchers will investigate how bacteria sense and respond to mechanical forces during cell growth and division to maintain cell wall integrity. The Engineering program aims to improve quality of life...
- The Massachusetts Institute of Technology (MIT) was awarded a $800,000 Project Grant from the National Science Foundation (NSF) to conduct collaborative research titled "Learning How Mucus Shapes and Maintains Microbiomes" from September 1, 2021 through August 31, 2026. Under the award, MIT researchers will work to advance understanding of the role that mucus plays in shaping and maintaining microbiomes. The research is funded through the NSF's Biological Sciences program (CFDA...
- This $1,230,301 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports a multidisciplinary collaboration to explore the mechanical properties and genetic/biochemical basis of a potent adhesive biopolymer produced by bacteria. The research aims to provide a detailed mechanistic understanding of how these types of materials impart strong adhesion, with applications in developing biocompatible and water-tolerant adhesives. The award,...
- Yale University received a $300,000 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), awarded on December 1, 2025, with a completion date of November 30, 2028. This collaborative research project delivers theoretical models and experimental analysis focused on understanding the mechanics and morphogenesis of bacterial biofilms as a model system for adaptive growth. The primary deliverables...
- Federal Project Grant Award Summary Columbia University received a $914,479 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through July 31, 2028. The award funds research to elucidate principles of microbiome spatial organization using a defined synthetic human gut microbiome (SYNHCOM) composed of curated common and ecologically important gut bacteria. The...
- The National Science Foundation awarded a $548,102 project grant under the Engineering (47.041) program to the University of Texas at Austin to develop a predictive framework for understanding how bacteria sense and respond to surface mechanics upon attachment. The three-year award beginning April 1, 2022 will support research using atomic force microscopy, high-throughput culturing, finite element modeling, quantitative confocal microscopy, and genetic manipulation to characterize the stresses,...
- The National Science Foundation awarded a $996,521 project grant under the Biological Sciences program (CFDA 47.074) to the Carnegie Institution of Washington for the period of April 1, 2021 through March 31, 2024. The goal of the research project is to scale single-cell physiology studies to better understand community stability in the natural gut microbiome. As part of this work, Johns Hopkins University will expand its microbiome curriculum to additional middle schools in Baltimore County...
- Cornell University was awarded a $1,317,788 project grant from the National Science Foundation Division of Integrative Organismal Systems to develop tools for host-microbiome protein-protein interaction discovery and establish sequencing-compatible ultra-high-throughput experimental screening approaches. The grant also supports the launch of annual bioinformatics hackathons for students centered on protein structure-inspired projects and the development of computational tools to assign...
- Federal Grant Award Summary The Pennsylvania State University received a $450,000 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective September 1, 2025, through August 31, 2028. This NSF-BSF (National Science Foundation-Binational Science Foundation) collaborative award will develop organ-on-chip predictive models to investigate the role of gut microorganisms...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $719,638 to Cornell University to conduct fundamental research on the nanomechanics of bacterial adhesion and growth on healthy and diseased human gut mucus. The research aims to determine how differences in the molecular structures of healthy and diseased gut mucus impact bacterial adhesion and biofilm formation. The project will use computational modeling and simulations to obtain nanoscale insights on these factors, with the goal of accelerating the design of mucoadhesive therapeutics or antimicrobials for treating human gut disorders. The award also includes an educational component, integrating engineering, biological, and humanistic sciences through an online summer course and partnerships with educational programs. No subawards are planned for this 5-year research effort, which began on August 1, 2024.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $719.6k | 3/11/24 |