Project Grant 2527720
Award Date
7/15/25
Completion Date
6/30/26
Dollars Obligated
$305K
Federal Agency
National Science Foundation
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Boston, MA 02130, USA
Similar Awards
This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) provides $275,000 to Dcan Biosciences LLC to develop an advanced microfluidic system for cancer diagnosis and monitoring. The system aims to isolate and assess circulating tumor cells (CTCs) and CTC clusters (CTCCs) from patient blood samples to enable highly sensitive and accurate liquid biopsies. Key objectives include designing a hybrid microfluidic device for...
This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Cerflux Inc. aims to develop a personalized cancer treatment screening platform. The project will establish guidelines for handling solid tumor biopsy samples, generate 3D bioprinted tumor models for validation, and demonstrate the platform's ability to match patients with the most effective cancer treatments before treatment begins. This innovative approach has the...
This Project Grant award of $449,996 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports a collaborative U.S.-U.K. research project to develop a highly sensitive, low-cost sensor platform for detecting circulating tumor DNA (ctDNA), a key biomarker for early cancer diagnosis. The project aims to combine microwave photonics (MWP) and polymer-based micro-ring resonator technology to create a portable and affordable solution for point-of-care cancer screening....
The National Science Foundation (NSF) awarded a $1,213,619 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Encapsulate Inc., a small disadvantaged business in Farmington, CT. This Phase II Small Business Innovation Research (SBIR) project aims to develop a precision oncology platform that integrates microfluidics, biochips, bioreactors, and 3D tumor models to predict patient-specific cancer drug responses. The proposed technology utilizes...
This National Science Foundation Project Grant of $255,995 supported Encapsulate Inc. to develop an automated biochip platform for personalized cancer screening under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The award period was from May 15, 2022 to April 30, 2023. The platform will grow patient-derived cancer cells outside the body on biochips to screen them against chemotherapy drugs. This addresses the problem that over 70% of cancer patients undergo ineffective...
This National Science Foundation (NSF) Project Grant award for $380,074, awarded on September 1, 2024, aims to develop a platform for instrument-free, easy-to-interpret quantitative analysis of molecular biomarkers. The project will produce a general methodology adaptable to a range of molecular targets, including potential new agents. The key products to be delivered include: A "yes/no" output for quantitative measurement, enabled through stoichiometry and negative cooperativity-based...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,990 to Scorpido Photonics aims to develop a prototype endoscope-based diagnostic system for rapid, non-invasive detection of microscopic tumors. The project integrates plasmonic nanobubble sensors into a medical device platform and standard endoscope to enable instant, optical detection of cancerous tissues during lung cancer diagnostic procedures. The key product is a...
This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...