Project Grant 2527479
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to characterize the contributions of transposable elements, or "jumping genes," to the human transcriptome. The $875,379 project, awarded to The Johns Hopkins University on August 1, 2025, aims to develop a deep learning model that can predict exonization of transposable elements directly from genome sequences, without the need for extensive gene and tissue...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 provides funding for a postdoctoral research fellowship from July 1, 2024 to June 30, 2027. The fellowship will support research and training to investigate the rules governing interactions between genomes, environment, and phenotypes, with a focus on understanding how repetitive DNA sequences, particularly a satellite repeat on the X chromosome of Drosophila melanogaster, influence...
- The U.S. National Institute of General Medical Sciences (NIGMS) awarded a $372,263 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Georgia Research Foundation, Inc. The grant, awarded on June 1, 2025, will support research to investigate novel mechanisms of retrotransposon regulation that limit transposable element (TE) mobility and horizontal transfer between species. The project aims to expand on the researchers' discovery of...
- This National Science Foundation Project Grant award of $1,324,710 provides funding from July 1, 2022 through June 30, 2025 to support research understanding how newly evolved genes acquire protein interactions and regulatory mechanisms in Drosophila reproduction. Funded under the Biological Sciences program (CFDA 47.074), the award to the College of the Holy Cross will explore how three genes essential for Drosophila melanogaster spermatogenesis evolved novel capabilities, including physical...
- This $452,399 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Hofstra University to investigate the epigenetic regulation of transposable elements in maize. The research aims to study the RNA-directed DNA methylation (RDDM) induced by naturally occurring maize "killer" alleles and explore the dynamic regulation of transposable element silencing in response to developmental cues. The project will...
- This $240,000 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) funds a postdoctoral research fellowship to investigate the role of genome organization on de novo gene origination. The research aims to test a new theoretical model explaining the process of new gene evolution, by examining how the genome's structural features influence the birth of genes that arise from non-coding regions. The key components of the research include: 1)...
- This $162,874 Project Grant award was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to The Trustees of Princeton University. The goal of this research project is to quantify protein dynamics and post-transcriptional regulation within the ectoderm germ layer of Drosophila (fruit fly) embryos. The researchers will use genetically modified Drosophila embryos expressing uniform morphogens to analyze...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 provides funding for a postdoctoral research fellowship focused on modeling gene drive with selfish germline stem cells in the Drosophila testis. The key products and services to be delivered through this 3-year project include: Identification of Chinmo protein binding sites on chromatin and Chinmo transcriptional targets in germline stem cells (GSCs) using CUT&RUN and...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program has awarded a $279,000 Postdoctoral Fellowship Project Grant to Dr. Galen Martin at Purdue University. The 3-year grant, which commenced on Jul 1, 2025, supports a research and training plan titled "Determinants of Evolutionary Success for Active Transposable Element Populations in the Maize Genomic Ecosystem." The project aims to investigate the proliferation of transposable elements, which...
- This Project Grant award, funded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074), aims to develop computational and experimental tools to facilitate real-time studies of RNA transport and localization in the fruit fly (Drosophila melanogaster) model system. The $594,125 award to Yeshiva University will be used to investigate connections between maternally deposited RNAs and intracellular vesicular trafficking via Rab family members during Drosophila...
The Project Grant award, titled "Identification of Host-Encoded RNA Binding Proteins that Promote P-Element Transposition," is funded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074). The project aims to identify host cellular proteins that regulate transposable elements (TEs), which are mobile genetic fragments that can cause DNA damage and harmful mutations in the host genome. The research will utilize new approaches to study the regulation of TE RNA, with a focus on the P-element DNA transposon in the genetic model Drosophila melanogaster. The $332,385 award, with a project period from September 1, 2025, to August 31, 2028, will support the development of genetic tools and the implementation of two target-oriented methods to identify the host proteins that bind and process TE RNA. The research findings are expected to advance the understanding of how host cells regulate the proliferation of TEs, which have significant implications for genome stability and evolution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $332.4k | 8/14/25 |