Project Grant 2526917
- This Project Grant award, funded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program, supports a collaborative research project to evaluate innate immune responses across vertebrate evolution, with a focus on the CD300 protein family. The $458,015 award to the University of North Carolina at Charlotte aims to map the molecular and functional diversification of CD300 orthologs and paralogs, and experimentally test ancestral CD300 functions. The research...
- The National Science Foundation (NSF) awarded a $2,057,185 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Florida to conduct research on the functional genomic dissection of biomineralization using a new marine model organism, the starlet sea anemone Nematostella vectensis. The overarching goal is to develop a novel platform for examining biomineralization at multiple scales, from the molecular to the organismal level. Key components include comparative...
- The National Science Foundation awarded a $817,970 project grant to The University of North Carolina at Charlotte under the Biological Sciences federal grant program (CFDA 47.074) for a three-year period from May 1, 2021 to April 30, 2024. The grant will support research studying the evolution of the antiviral pathway in a cnidarian model interacting with diverse viral communities. The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...
- This Project Grant award of $361,227.00 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program is funding research at the University of North Carolina at Chapel Hill (UNC-CH) to investigate the role of host immune systems in enabling beneficial bacterial symbioses across diverse insect species. The primary objective of this 16-month project is to use cutting-edge genomics and experimental manipulations to link immune responses with symbiont...
- This Project Grant award in the amount of $144,912 from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at North Carolina State University to investigate the factors shaping host-associated microbial communities using the honey bee as a model system. The research aims to integrate concepts from ecology and evolution to understand how environmental factors, species interactions, and evolutionary dynamics influence the composition of...
- This $425,486 federal Project Grant award to the University of North Carolina at Chapel Hill (UNC-CH) was made by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program. The project aims to study the evolutionary history and functional diversification of the CD300 gene family, which encodes immune receptors implicated in human health issues like cancer, inflammation, and viral infections. Using a multi-omic approach, the research will map the molecular and...
- This $502,071 National Science Foundation project grant supports research at the University of California, Merced to define metabolic complementation within the sea anemone microbiome. The research aims to advance understanding of how microbial communities cooperate to enhance the fitness, health and survival of eukaryotic hosts. Specifically, the three-year award will fund work to quantify the microbiome's impact on host fitness using gnotobiotic sea anemones, reintroduce isolated microbial...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to understand the assembly, diversification, and coevolution of microbiomes associated with marine invertebrates. The $590,677 award to New College of Florida aims to elucidate the rules governing host-microbe relationships across spatial, temporal, and taxonomic scales. The project is training graduate, undergraduate, and high school students in microbiome analysis,...
- This two-year Project Grant from the National Science Foundation (NSF) Division of Biological Infrastructure provides $138,000 to uncover the molecular mechanisms that govern cnidarian-algal symbiosis using forward genetic screens. Funded under the NSF's Biological Sciences program (CFDA 47.074), this award will support research to increase scientific knowledge and enhance understanding of major problems in the biological sciences. Using forward genetic approaches, the grantee will conduct...
- This NSF Biological Sciences (CFDA 47.074) Project Grant award of $600,000 to Emory University will investigate how microbiome communities, which are communities of bacteria and other microbes that live in and on organisms, can resist change and transition to alternate states. The project will use the nematode worm Caenorhabditis elegans as a model host to better define the stability and properties of alternate microbiome states, as well as how factors like antibiotic treatment and host...
This $650,970 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program will support research at the University of North Carolina at Charlotte (UNC Charlotte) to investigate the role of gene copy number variation in host-microbe interactions of a coastal sea anemone. The research team will utilize the sea anemone Nematostella vectensis as a model organism to study how variation in the copy number of key immune genes among individuals impacts the animal's survival, physiology, associated microbial community, and molecular responses. This integrative research approach aims to provide insights into how host species shape their microbiomes and respond to pathogens, which has implications for conserving species critical for aquaculture and ecosystem resilience. The project will also provide mentoring and training opportunities for STEM students at UNC Charlotte and engage the local community through a science museum partnership and a new university center focused on the intersection of biology, computation, and environmental health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $651.0k | 7/28/25 |