Project Grant 2517851
- This $200,000 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) will fund research into the environmental fate and infectivity of rotavirus and norovirus vesicles in wastewater and natural aquatic systems. The George Washington University will investigate the presence, persistence, and inactivation of virus clusters enclosed in fluid-filled sacs called vesicles, which have been shown to be more persistent, infectious, and resistant to disinfection than free...
- This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $497,000 in funding to the Rochester Institute of Technology (RIT) to conduct research on the mechanobiology of viral infections. The study aims to explore how mechanical forces, such as changes in tissue stiffness and cyclic strain, impact virus-cell interactions in lung tissue. Specifically, the research will investigate how matrix stiffness and cyclic strain affect viral infection...
- This Project Grant award of $481,250 from the National Institute of Allergy and Infectious Diseases (NIAID, CFDA 93.855 Allergy and Infectious Diseases Research) supports research to understand the mechanisms of human rotavirus (RV) egress and infection in association with extracellular vesicles (EVs). The project aims to characterize how RV interacts with EVs derived from human colonic epithelial cell lines (Caco-2 and HT29) to facilitate virus release, immune evasion, and enhanced infection of...
- This $400,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research to model the complex dynamics of viruses and bacteria in ancient ocean-like environments. The project aims to identify "keystone" viruses that significantly influence microbial community structure and biogeochemistry in these stable, oxygen-free lake ecosystems. The research will develop innovative mathematical methods to predict...
- This Project Grant award, valued at $1,153,105.00, was provided by the National Science Foundation's Geosciences Program (CFDA 47.050) to the University of Maryland Center for Environmental Science (UMCES). The award, titled "COLLABORATIVE RESEARCH: CONSTRAINING VIRUS LOSS AND CARBON AND NITROGEN FLOW THROUGH VIROVORY IN TEMPERATE MARINE ECOSYSTEMS WITH ISOTOPE TRACING AND MICROBIAL FOOD WEB MODELS", aims to investigate how virus grazing (virovory) impacts the cycling of organic matter...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) program provides $240,000 over 3 years to fund a postdoctoral fellowship focused on understanding how climate change-driven shifts in environmental conditions, such as increasing salinity, affect viral activity and its influence on microbial host genomes and phenotypes. The research aims to explore the large-scale impacts of these changes on microbial evolution and global biogeochemical...
- This National Science Foundation Project Grant of $365,556 supports collaborative research between mathematicians, biologists, and engineers at the University of Wisconsin-Madison to develop new mathematical tools and biological experiments essential to understanding virus spread and extinction. Funded through the NSF's Biological Sciences program (CFDA 47.074), the research will establish an integrated experimental-mathematical framework to study how spatial structure affects viral evolution...
- This $630,848 federal Project Grant award from the National Science Foundation's Geosciences Program (CFDA 47.050) supports collaborative research conducted by Bigelow Laboratory for Ocean Sciences to uncover previously undiscovered RNA virus populations within marine oxygen-depleted systems. The research aims to connect these viruses to their microbial hosts and characterize their role in exacerbating ocean deoxygenation and the production of greenhouse gases. The project incorporates...
- This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) Federal Grant Program provides $987,566 to the University of California, Los Angeles (UCLA) to conduct research on viral self-assembly, from test tube to cell cytoplasm. The award period runs from December 15, 2024 to November 30, 2028. The key objectives of this project are to elucidate the differences between in vitro and in cellulo viral processes by progressively adding molecules...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) federal project grant award of $270,000 provides funding for a postdoctoral research fellowship from July 1, 2025 to June 30, 2028. The fellowship supports research and training that will contribute to understanding how viruses, bacteria, and other pathogens influence the success or failure of invasive species, using wild rodent populations in New England as a case study. The research will generate a time transect of native...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $498,069 to the Research Foundation of the City University of New York to support research on microvesicle-mediated transmission of rotavirus. The project aims to technically characterize this newly discovered virus transmission mechanism and understand its evolutionary impacts. Key objectives include quantifying the number of viruses packaged per microvesicle, determining the proportion of defective viral particles, and comparing productivity of microvesicle-borne infections to traditional free-floating virus transmission. The research has significant global health implications, as rotavirus is a major cause of severe childhood diarrheal disease. In addition, the project will establish a new virology laboratory course at Queens College and provide immersive lab experiences for high school students to promote STEM career exploration. The award period runs from September 1, 2025 through August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $498.1k | 7/28/25 |