Project Grant 2517722
- This $400,000 Project Grant, awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041), is funding a collaborative research project at the University of Michigan to study the mechanics of tissue boundary formation. The research aims to explain how mechanical forces inside the body help shape developing tissues during early stages of life, by investigating how cells move, interact, and respond to mechanical cues during tissue formation. The 3-year project will combine...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
- Syracuse University has been awarded a $338,480 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) to develop a 3D computational model of epithelial stratification and turnover in skin tissue. The three-year award beginning May 1, 2023 will support the university's research using biophysical modeling and collaboration with cell biology experiments to quantitatively predict the mechanical response of self-renewing stratified epithelia. Specifically, the...
- This Project Grant award from the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation provides $390,593 to Syracuse University for research on the mechanoregulation of amnion patterning through activation of bone morphogenetic protein signaling. The 3-year project aims to study amnion development using a stem cell-derived human development model, with the goal of advancing knowledge in early human development and enabling the rational design of 3D stem...
- This federal Project Grant award, valued at $400,000.00, was made by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) to Cornell University. The project, titled "Morphogenesis by Design: An Integrated Mechanobiology Framework for the Sculpting of Architected Biological Tissues", aims to uncover the fundamental mechanistic principles of connective tissue morphogenesis and introduce computational design tools that would instruct the use of robotic...
- This $395,749 federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) will enable researchers at Syracuse University to develop a comprehensive physics framework for understanding how cell nuclei and tissues adapt to extreme mechanical stress. The project aims to investigate the mechanisms by which cell nuclei deform and respond to compression, as well as how tissue-level forces impact chromatin organization. The...
- This $199,982 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) funds research at Wesleyan University to investigate the principles governing the interactions at the interface between different groups of cells. The project aims to understand how cells from different tissues interact and organize themselves when they come into contact, which is crucial for advancing knowledge in areas such as tissue development, wound healing, and cancer...
- This $635,000 Project Grant awarded by the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation supports research to understand how mechanical boundary conditions influence tissue assembly and repair in 3D fibrous microtissues. The research aims to advance knowledge about the mechanisms by which mechanical forces regulate new tissue formation and organization, particularly as it relates to wound healing. The project will integrate in vitro experiments and...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $250,120 Project Grant to Clemson University to conduct collaborative research on the effect of cellular deformation on the proliferation and motility of single cells. The goal is to engineer specialized microfluidic devices to study how physical stresses experienced by cells in the human body, such as when they move and squeeze through tight spaces, impact their ability to divide and migrate. This research aims to...
- Syracuse University was awarded a $668,729 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation under the NSF Engineering program (CFDA 47.041). The award will support research into the biomechanics and mechanobiology of vimentin intermediate filaments and their role in cell motility and nuclear stability. Specifically, the university will investigate how vimentin enables cells to sense and respond to mechanical stresses, and study...
This $249,894 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports collaborative research at Syracuse University to study the mechanics of tissue boundary formation. The project aims to explain how mechanical forces inside the body help shape developing tissues during early stages of life. By combining expertise from biology and engineering, the research team will investigate how cells move and interact, and how mechanical forces guide their behaviors during tissue formation. This knowledge could lead to new technologies useful in other areas of science and medicine. The project also includes educational and outreach efforts to engage students at various levels and backgrounds, introducing them to the importance of STEM fields and inspiring them to consider careers in these areas.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.9k | 7/30/25 |