Project Grant 2515533
- This $791,029 Project Grant awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) program supports a collaborative research project titled "RUI: LIFE WITHOUT LIPOPOLYSACCHARIDE- SYNTHESIS OF CERAMIDE PHOSPHOGLYCERATE" at Rutgers, The State University of New Jersey, Camden. The project aims to discover how the ceramide lipid CPG2 is synthesized and understand its role in allowing gram-negative bacteria to survive without lipopolysaccharide (LPS) in their outer...
- This National Science Foundation Project Grant award of $997,716 provides funding from May 15, 2022 through April 30, 2026 to investigate the molecular mechanisms that maintain the integrity of the bacterial cell envelope under stress conditions. The award was made under the Biological Sciences program (CFDA 47.074) to the Research Foundation of the City University of New York at the City College of New York. Specifically, the awardee will examine how bacteria regulate the post-translational...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award, totaling $1,117,922.00, supports research to determine the mechanisms of bacterial tyrosine kinase activation and regulation. The Research Foundation of the City University of New York will utilize computational and experimental methods, including biochemical assays, NMR spectroscopy, and mass spectrometry, to investigate the activation of bacterial BY-kinases in both Gram-positive and Gram-negative...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund research to characterize the molecular mechanisms and evolution of cyclic diguanylic acid (c-di-GMP) signaling in the antibiotic-producing bacterial genus Streptomyces. The $383,746 award, with a performance period from January 1, 2025 to December 31, 2029, will be executed by Cornell University's Office of Sponsored...
- This Project Grant award, titled "CAREER: STRUCTURE AND FUNCTION OF LIPID ANTIGEN SELECTION AND PRESENTATION", was provided by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) Federal Grant Program. The project seeks to study how lipids and protein molecules assemble to carry out their biological functions, with a focus on developing new computational tools to model lipid/protein complexes and characterizing the mechanisms by which lipids interact...
- The Research Foundation For The State University Of New York (RF SUNY) was awarded a $953,119 Project Grant from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) to conduct fundamental research on the regulation and interaction of ceramides in cellular senescence and cell death processes using mammalian cell models. The award, issued on May 1, 2023 with a completion date of April 30, 2027, will support biochemical, chemical biological, and analytical approaches...
- This $1,230,301 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports a multidisciplinary collaboration to explore the mechanical properties and genetic/biochemical basis of a potent adhesive biopolymer produced by bacteria. The research aims to provide a detailed mechanistic understanding of how these types of materials impart strong adhesion, with applications in developing biocompatible and water-tolerant adhesives. The award,...
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences Federal Grant Program (CFDA 47.074) provides $493,916 to the Massachusetts Institute of Technology (MIT) to investigate how proteins and lipids coordinate the formation and function of membrane-associated condensates. The research aims to improve understanding of how the cell surface is organized, which could enable breakthroughs in biotechnology, disease treatment, and fundamental cell biology. The project...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $494,559.00 to the University of Delaware to conduct research on the bacterial cytochrome c biogenesis synthase function, specificity, and evolution. The project will obtain a detailed, mechanistic understanding of the bacterial System II cytochrome c biogenesis pathway through structure-function analysis. It will integrate undergraduate researchers into the...
- This $208,784 federal Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project to study the emergent dynamics and scaling laws of bioinspired lipid membranes. The University of Arizona, as the primary awardee, will integrate experimental methods such as neutron spectroscopy, NMR, and flicker spectroscopy with molecular dynamics simulations. This integrated approach aims to establish the...
This Project Grant award, provided by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program, is funding collaborative research to investigate the synthesis and role of the lipid ceramide phosphoglycerate (CPG2) in gram-negative bacteria. The $481,722 award will support research to discover how CPG2 is produced and explain the enzymes responsible, with the goal of understanding the various functions of bacterial lipids. This work will contribute to answering important basic and translational research questions related to lipid production and function in all bacteria, including disease-causing strains. The project will also train students at the high school, undergraduate, and graduate levels in genetics, biochemistry, and structural biology, developing the next generation of researchers and a strong biotech workforce. The award was made to The Research Foundation for the State University of New York, doing business as Stony Brook University, and has an anticipated completion date of August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $481.7k | 8/6/25 |