Project Grant 2514195
- This $480,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of novel approaches for assembling three-dimensional protein biomaterials. The primary goal is to create "coordinated protein frameworks" (CPFs) - extended protein lattices with defined geometries and tunable distances between the assembled proteins. This work leverages non-canonical amino acids to precisely control the...
- This federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) in the amount of $100,000 will support collaborative research to develop deep learning-based "consistency models" that can simulate protein dynamics over long time scales. The goal is to overcome the limitations of current molecular dynamics simulation methods, which are constrained by the need for tiny time steps, in order to unlock new insights into protein behavior and...
- The federal Project Grant award, valued at $697,510.00 and funded by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program, aims to improve, validate, and interpret amino acid substitution models for protein evolution. The research will enhance understanding of how substitutions of amino acids in proteins impact their form and function, which is critical for reconstructing the evolutionary history of proteins and advancing phylogenetic inference. The project, with a...
- The National Science Foundation awarded a $430,000 Project Grant to The Washington University in University City, Missouri under the Mathematical and Physical Sciences program (CFDA 47.049) from October 1, 2025 to September 30, 2028. The grant supports research to develop "bilingual biopolymers" - synthetic molecules that can simultaneously encode both nucleic acid and protein information. The project aims to modify the protein code of these biopolymers to control their assembly,...
- This Project Grant award for $140,390 was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research to develop porous peptide frameworks inspired by the modular architecture of proteins. The research aims to engineer these frameworks by appending peptides with aromatic π-stackers to guide the predictable self-assembly of the peptides into sophisticated porous materials. If successful, these...
- This Project Grant award, valued at $332,241.00, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049). The purpose of the award is to develop a generalized Poisson-Boltzmann (PB) theory that can accommodate non-rigid biomolecular structures, enabling PB models to better handle shape changes in key biological processes such as solvation and binding. The research will be conducted by the University of Alabama and...
- This Project Grant award, valued at $240,000.00, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research on the mechanics of non-Euclidean elastic thin sheets, with a focus on hyperbolic geometries that lead to spontaneously formed complex shapes found in natural soft materials such as leaves, flowers, sea slugs, and corals. The research aims to uncover the rules governing the shapes and...
- The National Science Foundation awarded a $568,044 Project Grant to Michigan Technological University from October 1, 2021 to September 30, 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). The grant supports collaborative research to predict molecular interactions that can stabilize viral therapies. The Mathematical and Physical Sciences program aims to advance scientific knowledge and enhance understanding of major problems through support of mathematical and physical...
- This Project Grant award of $500,000.00 from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support research by the University of Arkansas, Fayetteville to study the impact of biomolecule shape on the formation, stability, and composition of cellular compartments. The research aims to elucidate the fundamental mechanisms behind liquid-liquid crystal phase separation, with a focus on how the orientation-dependent interactions of rod-like particles affect this...
- This $180,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports research on the development of a broad, model-independent framework for studying complex invasion fronts, which play a key role in the self-organized development of coherent structures in scientific fields like epidemiology, developmental biology, and materials science. The project aims to make theoretical advances and develop computational tools to...
This $232,771 Project Grant, awarded on September 15, 2025, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program. The grant aims to develop computational mathematical tools to better understand protein structures and interactions, even across a wide range of mutations. This interdisciplinary research combines mathematical modeling, machine learning, and biology to analyze the complex shapes of proteins, with the goal of enabling faster and more accurate predictions about the infectivity of viral strains. The project supports education development by training students in the interdisciplinary studies of mathematics and biology. The research is being conducted by the University of Arkansas, Fayetteville Division, operating as the Office of Research & Sponsored Programs.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $232.8k | 8/25/25 |