Project Grant 2514164
- This $1,000,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports research by the University of California, San Francisco (UCSF) to design, build, and test synthetic signaling systems built from computationally-designed de novo protein components. The goal is to develop stable, tunable, and modular signaling systems capable of precisely controlling biological processes, with applications in biotechnology such as engineered cells for...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $361,277 Project Grant to the University of Chicago on January 15, 2021 to complete work by January 31, 2024. The grant supports collaborative research focusing a quantitative lens on synthetic phototrophic communities under the Biological Sciences program (CFDA 47.074). The program aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing...
- The National Science Foundation (NSF) awarded a $885,642 project grant under the Biological Sciences (CFDA 47.074) federal grant program to Trustees of Boston University. The grant will fund research to characterize signal propagation and control within gene regulatory networks using optogenetics. The goal is to define the underlying principles of network function and leverage this knowledge to create synthetic organisms for biotechnology, biomedicine, and agriculture applications. The project...
- This National Science Foundation (NSF) federal Project Grant award under the Biological Sciences program (CFDA 47.074) is funding the University of Illinois to construct a new type of self-replicating synthetic cell system. The $448,355 award from June 1, 2024 to May 31, 2027 supports the development of engineered synthetic cells that can grow, divide, and replicate their genetic information using nucleic acids as both structural and genetic components. The project aims to investigate the...
- This $803,678 Project Grant was awarded on August 15, 2025 by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program to the University of Wisconsin System to conduct research on synthetic induction of self-organized cell patterning and morphogenesis. The project focuses on understanding cell division events at the cell cortex, which is the primary driver of cell shape changes, in order to better comprehend pathological states like cancer, impaired healing,...
- The University of Chicago received a $360,114 project grant award from the National Science Foundation on October 1, 2021 to support research titled "COLLABORATIVE RESEARCH: DMREF: LIVING BIOTIC-ABIOTIC MATERIALS WITH TEMPORALLY PROGRAMMABLE ACTUATION" through September 30, 2025. The award is being administered under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific...
- This federal Project Grant award of $400,000.00 from the National Science Foundation (NSF) under the STEM Education (CFDA 47.076) program will support an REU (Research Experiences for Undergraduates) site program at Northwestern University from June 2025 to May 2028. The program will train approximately 30 students, primarily from schools with limited research opportunities, in the rapidly growing field of synthetic biology over three summer sessions. Students will conduct independent laboratory...
- The National Science Foundation (NSF) awarded a $510,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program to the University of Chicago. This 3-year award, with a project period from July 15, 2025 to June 30, 2028, supports research to design and explore "tempered dynamic covalent networks" - materials that can be reversibly altered to access a wide range of properties. The goal is to develop sustainable plastic materials that can be...
- This $448,150 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop a DNA-based toolbox for the rapid and precise modulation of cell membrane protein-protein interactions (PPIs). The goal is to establish a modular approach using antibodies and aptamers to enable targeted DNA barcoding of cell membrane proteins, particularly receptor tyrosine kinases. This will allow for the controlled stabilization of specific PPI pairs on living...
- This $200,348 Project Grant awarded by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CFDA 47.070) program supports the development of modular biological robots with variable morphology. The project aims to create functional modules controlled by different colors of light to enable new capabilities for "biobots" - robots fabricated from biological cells. Key goals include designing biobots that can split apart or join together on...
The National Science Foundation (NSF) awarded a $300,000 Project Grant under the CFDA 47.041 Engineering program to the University of Chicago. The grant, titled "BRING-SYNBIO: DYNAMIC COOPERATIVE BINDERS FOR ENDOGENOUSLY GATED CELLULAR CONTROL," aims to develop a new class of molecules that can directly sense environmental cues and rapidly trigger targeted cellular responses. This innovative synthetic biology research seeks to establish a platform for engineering dynamic, gated circuits that can infiltrate existing cells and alter their behavior, such as directing tumor cells to break apart and die. The project will also include outreach efforts at the local Southside Chicago Science Festival to engage the community and attract students to STEM careers. The award period is from October 1, 2025, to September 30, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.0k | 8/18/25 |