Project Grant 2512104
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) federal grant program provides $174,976 to Clemson University from September 1, 2025 to August 31, 2028. The project aims to develop generalized Poisson-Boltzmann theory to accommodate non-rigid biomolecular structures, enabling computational models to better handle shape changes in biological processes like solvation and binding. The new computational tools will be...
- This $232,771 Project Grant, awarded on September 15, 2025, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program. The grant aims to develop computational mathematical tools to better understand protein structures and interactions, even across a wide range of mutations. This interdisciplinary research combines mathematical modeling, machine learning, and biology to analyze the complex shapes of proteins, with the goal of enabling...
- This $298,435 federal Project Grant award from the National Science Foundation Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049) aims to provide the research community with a robust and versatile computational framework for accurate modeling of mesoscale bionano systems. Specifically, the project transforms the Atomic Resolution Brownian Dynamics (ARBD) code into a general-purpose mesoscale simulation engine supporting parallel computing on...
- This Project Grant award, valued at $600,000.00, was provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program to support the research of Dr. Dmitry Matyushov of Arizona State University. The award will fund the development of theoretical models and computational algorithms to address the problem of statistics and dynamics of interfacial fluctuations affecting interfacial screening, colloidal mobility, dynamics of electrolytes, and...
- This National Science Foundation Project Grant of $536,946 will support research at the University of California, San Diego from September 2022 through August 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). The award will fund the development of rigorous scientific theories and powerful computational tools to model biomolecular interactions. Researchers will design advanced numerical methods to simulate drug and protein binding/unbinding kinetics, incorporating molecular...
- This $480,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of novel approaches for assembling three-dimensional protein biomaterials. The primary goal is to create "coordinated protein frameworks" (CPFs) - extended protein lattices with defined geometries and tunable distances between the assembled proteins. This work leverages non-canonical amino acids to precisely control the...
- This Project Grant award, valued at $240,000.00, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research on the mechanics of non-Euclidean elastic thin sheets, with a focus on hyperbolic geometries that lead to spontaneously formed complex shapes found in natural soft materials such as leaves, flowers, sea slugs, and corals. The research aims to uncover the rules governing the shapes and...
- This $248,461 Project Grant award was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award will support research to efficiently design patchy particles for targeted assembly of bulk and finite soft materials structures, using state-of-the-art data-driven methods. The project aims to develop a fast design pipeline for building blocks that could potentially be synthesized in a laboratory environment. The...
- This $350,000 federal Project Grant was awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program. The goal of the research is to develop accurate mathematical models and computer simulations for studying non-equilibrium systems with memory effects, such as those found in biosystems, plasma evolution, and solid-state nanostructures. The Principal Investigator will focus on analytical and numerical approaches to statistical transport...
- This Project Grant award for $140,390 was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research to develop porous peptide frameworks inspired by the modular architecture of proteins. The research aims to engineer these frameworks by appending peptides with aromatic π-stackers to guide the predictable self-assembly of the peptides into sophisticated porous materials. If successful, these...
This Project Grant award, valued at $332,241.00, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049). The purpose of the award is to develop a generalized Poisson-Boltzmann (PB) theory that can accommodate non-rigid biomolecular structures, enabling PB models to better handle shape changes in key biological processes such as solvation and binding. The research will be conducted by the University of Alabama and is expected to be completed by August 31, 2028. The new computational tools developed under this award will be made freely available to the broader biological research community, and the project will also provide interdisciplinary research and training opportunities for students. Outreach activities are planned to engage the public and foster understanding of how computational science contributes to human health and biomedical innovation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $332.2k | 8/7/25 |