Project Grant 2505720
- The National Science Foundation Division of Chemistry awarded a $1,010,000 project grant to the University of Texas at Austin to develop innovative mass spectrometry methods for characterizing intact proteins through June 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). Professor Jenny Brodbelt and her research group will apply ultraviolet photodissociation and other dynamic ion manipulation strategies to amplify structural and post-translational modification details...
- The University of Texas at San Antonio received a $403,830 project grant award from the National Science Foundation Office of Integrative Activities under the Mathematical and Physical Sciences program (CFDA 47.049) to acquire a next-generation high-resolution mass spectrometer with ion mobility separation. The mass spectrometer will allow researchers to separate and analyze complex mixtures of biomolecules with unprecedented resolution from August 1, 2021 through July 31, 2022. The new...
- The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the Regents of the University of Michigan under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new high-throughput technologies for characterizing the 3-dimensional structures of proteins and RNA. Specifically, the funding will support Professor Brandon Ruotolo and his research team in expanding the capabilities of Collision Induced Unfolding (CIU) - an approach that uses...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $194,513 to Louisiana Tech University to acquire a MALDI-TOF mass spectrometry instrument. This multi-user instrument will support the research of 6 professors across disciplines including biochemistry, molecular biology, engineering, and polymer science. It will enable detailed analysis of a wide range of macromolecules, including polymers, peptides/proteins,...
- This $559,842 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry under the CFDA Program 47.049 - Mathematical and Physical Sciences supports the development of theoretical models and computational data analysis tools by Dr. Dmitrii E. Makarov of the University of Texas at Austin. The research aims to decipher the fundamental mechanisms of biomolecular motions and the efficiency of molecular machines through a synthesis of chemical theory, computational...
- The National Science Foundation (NSF) Division of Chemistry awarded a $500,000 Project Grant titled "TOPICS IN PROTEIN AND RNA FOLDING AND DYNAMICS" to the University of Texas at Austin under the Mathematical and Physical Sciences program (CFDA 47.049). This 4-year grant will support Professor Devarajan Thirumalai's research on the computational modeling of protein and RNA interactions and dynamics. Key focus areas include developing new methods to simulate intrinsically disordered...
- This federal Project Grant award, valued at $476,385.00 and funded by the National Science Foundation's (NSF) Division of Chemistry, supports a collaborative research project between Professor Michael Marty's team at the University of Arizona and industrial partners at Genentech, Inc. The project aims to develop new computational algorithms and experimental methods for improved analysis of complex mass spectrometry data, particularly focused on enabling more widespread use of intact mass...
- This $390,000 National Science Foundation Project Grant, awarded under the Mathematical and Physical Sciences program (CFDA 47.049), will support the development of Absolute Quantitative Protein Footprinting Mass Spectrometry (AQPFMS) for probing protein three-dimensional structures. Professor Hao Chen of the New Jersey Institute of Technology and collaborator Xiaolin Cheng of Ohio State University will refine an approach using AQPFMS to provide quantitative analysis of solvent-accessible...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $500,645 to Texas A&M University to develop new instrumentation and tools for measuring chemical and biological species at the nanometer scale. Specifically, the research will integrate electrochemical imaging and optical imaging techniques to study chemical and biochemical processes related to neuronal communication, wound healing, and molecular biology....
- The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), has awarded a $749,999 Project Grant to Princeton University and San Diego State University. The grant will fund the development of a novel method for tracking the synthesis, localization, and dynamics of RNA messages in living cells using metabolically incorporated fluorescent nucleosides. This innovative approach will enable researchers to study the organization of cellular structures...
This Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $630,000 in funding to the University of Texas at Austin to develop innovative mass spectrometry methods for characterizing nucleic acid structures. Professor Jennifer S. Brodbelt and her research group will design and implement new analytical techniques that integrate high-performance mass spectrometry and ion mobility separations to elucidate the structures and interactions of nucleic acids, which have many emerging applications in areas like therapeutics and data storage. The project will leverage laser-based photoactivation to dissociate nucleic acid ions and pinpoint structural modifications with high sensitivity. This research effort aims to advance the fundamental scientific understanding of nucleic acids and train students as future scientific leaders in this area. The award period runs from February 1, 2026 to January 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $630.0k | 8/26/25 |